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Biomedical subjects

I McConachie

Publications and source records attributed to I McConachie.

13 recordsLinked to original sources

Vasovagal asystole during spinal anaesthesia.

A patient in whom vasovagal asystole was induced by the performance of a spinal anaesthetic in the upright position is described. This illustrates the importance of routine monitoring of the electrocardiograph during regional anaesthesia. The risk of vasovagal syncope may be increased by the use of the sitting position and by the omission of anxiolytic premedication.

Adult

Effect of anaesthesia on the QT interval.

A prolonged electrocardiographic QT interval may be harmful during general anaesthesia. It may be prudent, therefore, to select anaesthetic agents which have the least effect on the QT interval. In a controlled study, propofol has been shown to have less effect on the QT interval than thiopentone (P less than 0.05). Our data suggest also that any effects which may be caused by enflurane and isoflurane are masked by the effects of the induction agent.

Anesthesia, General

Thiamine status after major trauma.

A prospective study of thiamine status in patients with severe injuries (injury severity scores greater than 12) showed that they all developed signs of severe thiamine deficiency on the basis of transketolase activity, the standard biochemical test for thiamine deficiency. This occurred within the first week after their injuries despite routine enteral or parenteral feeding including vitamin supplements. This may be due to increased requirements secondary to increased metabolic activity or increased cellular losses. An increased awareness of thiamine requirements and metabolism is essential to avoid the appearance of deficiency syndromes.

Adult

Ilioinguinal nerve blockade for analgesia after caesarean section.

Bilateral ilioinguinal nerve blockade was performed, using 0.5% plain bupivacaine 10 ml to each side, in 13 patients having elective Caesarean section under general anaesthesia. Pain scores and requirement for postoperative analgesia were compared with 13 patients in a control group. Pain scores were less in the block patients at all times during the first day after operation, with the exception of 12 h. There was an increased time from the patient's recovery from anaesthesia to the first injection of opioid in the block group. In the control group, patients required more analgesia in the first 24 h after surgery compared with patients having ilioinguinal nerve blockade. There were no observed adverse effects following nerve blocks.

Anesthesia, General

Value of pre-operative carotid sinus massage.

The usefulness of carotid sinus massage in pre-operative assessment is discussed with case examples. The technique and risks of carotid sinus massage are described. Carotid sinus massage is of particular value in the demonstration of sino-atrial and atrioventricular node disease in the absence of definitive abnormalities on the routine resting electrocardiogram, and in the identification of patients who show a hypersensitive response to vagal stimulation. These patients should be identified prior to procedures that involve marked vagal activity, since prolonged sinus arrest may occur.

Aged

Pacemaker assessment for junior doctors.

Recent experience at the Merseyside Regional Pacemaker Centre has emphasized that many junior doctors are unfamiliar with numerous important facts regarding permanent pacemakers. It is important to detect quickly a fault in a permanent pacemaker if, for example, a patient presents with recurrent dizziness, blackouts or a cerebrovascular accident.

Anesthesia