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Biomedical subjects

I Meizner

Publications and source records attributed to I Meizner.

At least 91 records · Page 5Linked to original sources
PubMed1990

Familial congenital diaphragmatic defect and associated midline anomalies: further evidence for an X-linked midline gene?

We report on familial occurrence of congenital diaphragmatic defect and associated midline anomalies, namely cleft palate and omphalocele in brothers. This family further supports the existence of an X-linked gene involved in the organization of the embryonal midline. This particular mutant gene might be active in the schisis-morphogenesis phenomena occurring at the midline.

Cleft Palate↗
PubMed1990

Niemann-Pick disease associated with nonimmune hydrops fetalis.

The number of metabolic disorders associated with nonimmune hydrops fetalis is very small and includes only Gaucher disease, GM1 gangliosidosis type 1, Hurler syndrome, and mucolipidosis type I. We report another association of a nonimmune hydrops fetalis with Niemann-Pick disease as evident by electron microscopy, and wish to add this disorder to the list of conditions associated with nonimmune hydrops fetalis.

Female↗
PubMed1990

Energy expenditure in normal labor.

The energy expenditure in 23 healthy parturient women during spontaneous labor was assessed by continuous measurement of their O2 consumption and CO2 production. Due to the intermittent character of uterine contractions, normal labor and delivery did not impose high energy demands on the parturient, whereas a prolonged labor and delivery in which energy input was high led to maternal metabolic disturbances.

Adult↗
PubMed1989

In utero prenatal diagnosis of Beckwith-Wiedemann syndrome; a case report.

The Beckwith-Wiedemann syndrome is an unusual complex of abnormalities that includes mainly omphalocele, macroglossia, natal and postnatal gigantism, visceromegaly and neonatal hypoglycemia. A case is presented where sonographic prenatal diagnosis of this rare condition was made. Prenatal findings and postnatal management are described.

Beckwith-Wiedemann Syndrome↗
PubMed1989

The combined suppression/stimulation therapy in IVF-ET programmes: expectations and facts.

The benefits of combined pituitary suppression/ovarian stimulation therapy in IVF-ET programmes could be avoiding an untimely LH secretion, synchronization of the ovarian response to stimulation, an increased number of ova obtained and embryos replaced and a higher pregnancy rate. The first two advantages can be considered as direct effects of the combined therapy, while the others result, at least partly, from the more aggressive use of gonadotrophins. The capability of combined GnRH analogue/gonadotrophin treatment to avoid failures due to premature luteinization of follicles seems to be unequivocal. In order to obtain a better synchronized ovarian response to stimulation, new treatment schemes, based on prolonged use of currently available agonists or on application of potent synthetic GnRH antagonists, will have to be developed. Basic studies concerning the presence and the extent of a direct effect of GnRH analogues upon ovarian function would also help in a better understanding and more efficient application of the combined suppression/stimulation therapy in IVF-ET programmes.

Embryo Transfer↗
PubMed1989

Reduction or cessation of fetal movements after steroid administration for enhancement of lung maturation. II: Analysis of blood flow velocimetry.

Reduction or cessation of fetal movements after intra-uterine exposure to pharmacological doses of steroids administered for enhancement of lung maturation has been previously reported. In the present study fetal activity and umbilical and uterine blood flow velocimetry in 18 pregnant patients receiving steroids were evaluated by ultrasonography. Measurements were done before, during and after steroid exposure in an attempt to clarify the possible pathophysiology of this peculiar change in intra-uterine fetal behavior. Even in cases in which mothers ceased to perceive fetal movements, on real-time sonography fetal activity was observed. The possible explanation for this phenomenon may be the influence of large doses of steroids that affected skeletal muscular activity. No changes in blood flow velocimetry in both uterine and umbilical arteries were observed throughout the study period, thereby indicating that the changes in fetal movements did not result from an altered blood supply.

Betamethasone↗
PubMed1988

Results of in vitro fertilization in women with antisperm antibodies in serum, cervical mucus, and follicular fluid.

This study was undertaken to investigate the presence of antisperm antibodies (ASA) in serum, cervical mucus, and follicular fluid (FF) of women undergoing in vitro fertilization and embryo transfer (IVF-ET). IgG and IgA ASA directed mostly against sperm head were found at similar concentrations in serum, cervical mucus, and FF of 2 of 34 patients. Ninety-one percent fertilization and 100% cleavage rates, respectively, were observed in one of the two patients. No fertilization occurred in the second patient. In both women, in vitro sperm penetration tests revealed hostile mucus and repeated postcoital tests were poor. It is concluded that the sperm-cervical mucus penetration test and mucus ASA measurements are useful in establishing the diagnosis of immunological infertility.

Adult↗