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Biomedical subjects

I Mendoza

Publications and source records attributed to I Mendoza.

31 records · Page 2Linked to original sources

Bioelectrical impedance spectroscopy (BIS) in young children with acute and semi-acute hydration disorders: potentials and limitations.

This study aimed to evaluate the feasibility and reliability of bioelectrical impedance spectroscopy in young children suffering of acute hydrational disorders. Whole body and segmental measurements were carried out in a group of 42 of children aged 4 to 147 months, using a BIS analyzer (Xitron 4000B). This phase of the study involved several hundred of BIS measurement, which showed the feasibility of using this technique in young children. Using the sweep mode and the modeling software provided for the manufacturer of the instrument, the resistance of the extracellular (RECW) and intracellular (RICW) compartment was calculated. Correlation coefficient (r) and technical error of measurement (TEM) were obtained from paired BIS measurements. RECW showed to be highly reproducible (r = 0.99), with a relatively low TEM (from 1 to 3.5%), across all segments. The reliability was markedly lower respect to RICW, which shows the potential application of BIS technique even in critically ill young child populations.

Acute Disease↗

[Introduction of Bacillus sphaericus strain-2362 (GRISELESF) for biological control of malaria vectors in Guatemala].

Malaria continues to be an important health problem in a number of countries of Central and South America where it is considered as a highly prevent endemic disease. The objective of this paper is to assess the entomo-epidemiological impact of a pilot program for the biological control of malaria-transmitting vectors, which was implemented in 1998 in Escuintla, Republic of Guatemala. This program was based on the use of 20,000 L of biolarvicide Bacillus sphaericus- strain-2362 (GRISELESF) which was applied in the 46 localities of highest epidemiological risk at a rate of 10 mL/m2 of effective area of breeding. The entomologic effectiveness of this biolarvicide was monitored from the first 72 hours to 4 months after the application. There was a total larval reduction of 94.57 in the maturity stage of the water phase of Anopheles albimanus vector. The epidemiological analysis was carried out by comparing the rate of malaria prevalence (per 1000 pop) during 1997 and 1998. The five treated municipalities showed a statistically significant reduction of 50% (p 0.01). The results obtained in this paper coincided with those reported by comparable studies, so, this allowed us to recommend the use of the biolarvicide Bacillus sphaericus (strain-2362) as part of a comprehensive program of malaria-transmitting vector control in the Republic of Guatemala and other countries of the region.

Animals↗

[Suppression, capture and modulation of ventricular parasystole].

Few clinical studies have dealth with annihilation, entrainment and modulation of ventricular parasystolic rhythm. Parasystolic modulation was diagnosed in 9 nonmedicated patients because single, nonparasystolic beats falling during the initial 59% of the cycle prolonged the parasystolic cycle length (by 12 to 37.5%), whereas those that fell later in the cycle shortened it (by 9 to 25%). Plotting this prolongation or shortening as a function of the temporal position of the nonparasystolic beats in the cycle, yielded biphasic response curves. In two patients, episodes of concealed one-to-one entrainment were initiated by late nonparasystolic (sinus) beats and, later on, terminated by early ventricular extrasystoles. In 2 other patients, (and in 2 separate occasions) nonparasystolic beats, falling in part of the cycle located in between those of maximal delay and acceleration, produced pacemaker annihilation (cessation of automatic activity for the remaining monitoring time). Parasystolic annihilation and concealed entrainment may be one of the causes that can explain the large, spontaneous, day-to-day variability in the incidence of ectopic ventricular beats reported in Holter recordings.

Arrhythmias, Cardiac↗

[Electrophysiological evaluation of the treatment of patients with recurrent ventricular tachycardia].

In order to asses the predictive value of serial electrophysiologic studies in the selection of an effective long-term effective antiarrhythmic regimen, we studied 16 patients with recurrent sustained ventricular tachycardia (VT), resistant to conventional medical treatment. (group 1) Eleven patients in this group had chronic chagas myocarditis, and several hospitalizations and cardioversions had been required for therapy of VT. In addition, 35 patients (group 2: control) underwent electrophysiological studies to evaluate rhythm disturbances differences to TV. Ventricular Tachycardia was successfully initiated and terminate with programmed electrical stimulation of the right ventricle only in the group 1. After control studies, the effects of several drugs (ajmalin, amiodarone, carbamazepine, disopyramide, diphenilhydantoin, mexiletine, procainamide, propranolol, quinidine and verapamil on the ability to initiate VT were assessed. A drug was considered effective only if it prevented the initiation of VT and allowed long-term suppression o clinical VT. All the patients of group 1 were placed on chronic oral therapy with the effective agent and were followed for an average period of 16 months (range 5 to 47 months). In all 16 patients we could document complete long-term prophylaxis against VT. This method offers advantage in terms of morbidity, mortality, duration of therapy, and promptness of choosing an effective drug add expense to the patient over traditional empirical methods of drug selection.

Adolescent↗

[Simultaneous maternal and infant care or rooming-in care in the General Hospital of Mexico of the S.S.A].

This paper presents the preliminary results of a prospective study undertaken at the Neonatal Unit of the Hospital General de México, S.S.A. (Méx.) conducted to evaluate the possibilities offered by the rooming-in system in this hospital. In both groups, having 250 patients, most of them eutrophic, it was noticed that none of the babies assisted by their mothers showed severe infections, as compared to four babies that showed clinical data compatible with septicemia; these babies were assisted in the nursery in a traditional way, but three of them died. Many of the aspects about the rooming-in system are reviewed, concerning the mothers as well as the babies, and it is finally determined that it is a practical, accessible system that optimizes resources and seems to offer immediate benefits to the mothers as well as to the babies.

Adolescent↗