Biomedical subjects
I Mikhaĭlov
Publications and source records attributed to I Mikhaĭlov.
[Antiviral action of derivatives of 1,3,4-oxadiazine on reproduction of type A influenza viruses in vitro].
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[Antiviral action of derivatives of 1,3,4-oxadiazine on the reproduction of type A influenza viruses in vivo in white mice].
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[Hormonally active pheochromocytoma].
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[Cytological differences in cell cultures infected with classical fowl plague virus and influenza virus type A].
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[Diagnosis and treatment of disseminated intravascular coagulation in pathological pregnancy].
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[Nuclear bodies of lymphocytes in the lymph nodes of guinea pigs treated with phytohemagglutinin in vivo].
Nuclear bodies (NB) were studied in guinea pigs regional lymph node cells after a single subcutaneous application of Phytohaemagglutinin Difco (PHA). A distinct reaction of the lymph node cells was established on the 3rd, 6th and 9th days consisting of increased number of lymphoblasts and large basophilic cells (LBC). Ultrastructural descriptive and morphometric methods were used. Authors revealed nuclear bodies to be present mostly in activated lymph node cells (lymphoblasts and LBC). Predominance of NB having RNP particles (complex type NB) was found. Simple NB (without RNP particles) had been seen rarely in small (resting lymphocytes. It was established NB to be larger, but leis im member. It is discussed on the participation of NB (Complex type) in the nuclear part of the protein synthesis.
[Frequency and complications of cholelithiasis].
The authors studied a total of 16557 necropsy reports for 20 years, at the Chair of Pathologic Anatomy, Medical Faculty, Sofia, as regards the incidence and complications of cholelithiasis. In order to determine the effect of the applied modern antibiotic treatment, the material studied covers the decades 1932-1941 and 1963-1972. Cholelithiasis incidence grew about five times during the second period. A change in the incidence of certain complications is also observed--a) there is a considerable decrease in the number of liver abscesses during the antibiotic period (about three times); b) the number of the developed biliary cirrhosis grew (about three times). With age aspect, the peak incidence has shifted with a decade backwards during the second period, life prolongation being the reason for it.