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Biomedical subjects

I Mizsei

Publications and source records attributed to I Mizsei.

7 recordsLinked to original sources
PubMed1990

[Stress tolerance in patients with right ventricular infarct during the rehabilitation period].

199 patients with myocardial infarction were divided into 4 groups according to the localisation of necrosis (anterior, inferior, anterior + right ventricle, inferior + right ventricle). Exercise capacity was determined by bicycle ergometer test at the beginning of rehabilitation and 3 weeks later. Exercise capacity and ejection fraction were better in case of inferior comparing with anterior infarction. There was no significant change in exercise capacity whether inferior or anterior left ventricle necrosis was accompanied by right ventricle infarction. In chronic phase of myocardial infarction exercise capacity of patients is not influenced by right ventricle necrosis accompanied by left ventricle infarction.

Exercise Test↗
PubMed1985

Pocket calculator program of one-way analysis of variance.

This program has been written for the TI-59 pocket calculator. It uses Bartlett's test to supervise the homoscedasticity, then performs the one-way analysis of variance and multiple comparisons, namely Scheffé's test, Dunnett's test, Turkey's test and Newmann-Keuls's test.

Analysis of Variance↗
PubMed1984

Effect of steroids on ACTH release from cultured pituitary cells of the rat.

Using a primary cell culture of rat anterior pituitary and corticotropin (ACTH) RIA, the effects of various steroids have been investigated. Dexamethasone inhibited the ACTH release stimulated by alpha-melanotropin and Pitressin (posterior pituitary extract), but did not influence the non-stimulated release. The effect of all the investigated steroids was significant; aldosterone exhibited a more marked inhibition than spironolactone. Simultaneous administration of aldosterone and spironolactone resulted predominantly in the manifestation of spironolactone action. A new effect of spironolactone has been demonstrated in vitro; the evaluation of its pharmacological importance requires studies in vivo.

Adrenocorticotropic Hormone↗
PubMed1983

Inhibition of corticotropin release in vitro by dexamethasone, aldosterone and spironolactone.

Dexamethasone, aldosterone and spironolactone inhibited the release of immunoreactive corticotropin (ACTH) from primary culture of the rat anterior pituitary cells. The steroids inhibited only the ACTH release stimulated by Pitressin and not the basal ACTH release by non-stimulated cells. On a molar basis, aldosterone appears to be the most efficient inhibitor of ACTH release while the effect of spironolactone is similar to the effect of dexamethasone. Simultaneous incubation with aldosterone and spironolactone inhibited the ACTH release to the same extent as spironolactone alone. This indicates that aldosterone's effect on ACTH release is also inhibited by spironolactone at the pituitary level.

Adrenocorticotropic Hormone↗