Clozapine treatment and risk of unplanned pregnancy.
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Biomedical subjects
Publications and source records attributed to I Modai.
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In 1984-85 Operation Moses brought a mass immigration of Jewish Ethiopians to Israel. Many of these immigrants were children and adolescents who came on their own having left their families behind. Since that time the adolescent department at the Geha Psychiatric Hospital has had the major responsibility of caring for those Ethiopian adolescents who required psychiatric hospitalization. The present study compares the diagnoses and reasons for admission of Ethiopian adolescents in Israel with those of Ethiopian adults and Israeli adolescents. The results of this comparison show that Ethiopian adolescents in hospital had significantly higher rates of dissociative disorders than the other two groups and significantly lower rates of the major functional psychoses than Ethiopian adults and Israeli adolescents. In addition the Ethiopian adolescents had relatively low levels of nonspecific depressive symptoms and anxiety symptoms and were hospitalized for significantly shorter periods of time than the other two groups.
We evaluated the contribution of a computerized laboratory alerting system to patient care in a 34-bed psychogeriatric unit. With this system the results of routine laboratory tests are automatically retrieved and registered on a daily computer-based medication report. During the first 33 days in which the alerting system was in use, a senior psychiatrist monitored the total number of alerting messages sent, the number of new messages per day, the number indicating physician unawareness, the number already dealt with, and the number that initiated a decision to treat the patient or repeat a laboratory test. The alerting system retrieved a mean (+/- SD) of 0.77 +/- 0.11 messages per patient per day. Twelve percent were new messages and 88% were rotating messages. Three resident psychiatrist-case managers were unaware of half the rotating messages (i.e., 6% of all messages). Seven percent of the new messages initiated treatment, and 15% resulted in laboratory retesting. We conclude that the alerting system results in a simple, efficient report that contributes substantially to safe patient care.
Twelve male schizophrenic outpatients treated with neuroleptics took part in an open-label drug study to assess the impact of co-administration of amantadine hydrochloride (100 mg daily for 6 weeks) on sexual function. Amantadine improved the patients' scores in three out of four areas of sexual function: desire (p < 0.02), erection (p < 0.05), and satisfaction from sexual performance (p < 0.05); there was no change in ejaculatory function. Amantadine may be effective for improving sexual function in male schizophrenic patients receiving neuroleptic medication.