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Biomedical subjects

I N Krupka

Publications and source records attributed to I N Krupka.

7 recordsLinked to original sources

[Comparative analysis of pancreatic scintigraphy and results of surgical treatment of patients with pancreatic cancer].

The results of radiologic investigation in 47 patients admitted to the clinic for pancreatic cancer were compared with the findings of the performed operative intervention. Visualization of the pancreas with 75 Selenomethionine was performed on the gamma-camera FO-GAMMA-IV (USA). A number of differential diagnostic signs of the pancreatic pathology was revealed, dependence between the character and degree of pancreatic changes on a scintigram, and volume of the operative intervention performed was noted. A variant of computerized processing of scintigrams with regard to the activity of the administered radiopharmaceutical preparation is suggested.

Adult

[Prognosis of the development and prevention of primary post- operative peptic stricture of the esophagus].

Examined were 58 patients with primary postoperative peptic esophageal stricture (PPPES). The ulcer disease of pyloroduodenal location and impaired function of the esophagus were the leading causes of a stricture. The prognostic algorithm for the PPPES development, which considers the presence of hiatal hernia, severe disorders in gastric evacuation and vomiting, pronounced weakness of a patient, severe complications of the ulcer disease before the operation, has been developed. The prophylactic measures in given pathology are suggested.

Adolescent

[A system for the automatic processing of radionuclide research (the SAORI-01) in clinical practice].

The author described the results of clinical testing of a system CAOPH-01 designed for automated collection, storage and processing of data on radionuclide investigations. He gave examples of automated processing of RCG and the results of positive scintigraphy of tumors of different sites using 67Ga-citrate and 99mTc-pertechnetate in statistical and dynamic investigations. Short-comings and ways for updating 4 the system during its serial production were pointed out. The introduction of the system into clinical practice on a wide scale was shown to hold promise.

Computer Systems

[Dynamics of carcinoembryonic antigen in patients with stomach cancer during treatment with cryotherapy].

Radioimmunologic assays of blood serum carcinoembryonic antigen (CEA) level were conducted at major stages of treatment of gastric cancer by subtotal stomach resection and gastrectomy with preliminary cryotreatment and thawing of tumor. A short-term rise in CEA level occurred in 53.9% of cases 3-4 days after combined therapy. A decrease in CEA concentration at discharge from hospital as compared with preoperative level and that registered 3-4 days after operation was observed in 50 and 75% of cases of combined therapy, respectively, and 47.5 and 37.5% of controls (surgery without cryotreatment). There was no correlation between cryotreatment and changes in CEA level in gastric ulcer patients.

Carcinoembryonic Antigen