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Biomedical subjects

I N Loshkomoeva

Publications and source records attributed to I N Loshkomoeva.

4 recordsLinked to original sources

[Effect of a varying ascorbic acid allowance in guinea pigs on the metabolic indices in their bodies to cold exposure].

Changes in the content of ascorbic acid in the blood, urine and suprarenals and also of glucose and 11-oxycorticosteroids in guinea pigs with different vitamin C allowances under conditions of cold stress were studied. The data obtained suggest that the degree of the vitamin C allowances is essential for adequate reactions of the organism exposed to the action of cold, but the shifts in metabolic transformations point to the need for a more reserved utilization of high ascorbid acid doses.

11-Hydroxycorticosteroids↗

[Free radical lipid oxidation and several ways of regulating it with ascorbic acid].

The correlation between the content of primary molecular product of free radical fat acyls oxidation--hydrolipid peroxidation and ascorbic acid amount in guinea-pig tissue was presented by means of polarographic method. The data obtained led to the following conclusion: the importance of ascorbic acid as prooxidant in vivo is rather great and its deficiency is the reason for an increase of its content in the primary products of lipid free radical oxidation, which probably plays the main role in C-avitaminosis pathogenesis.

Animals↗