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I N Mikhailov

Publications and source records attributed to I N Mikhailov.

4 recordsLinked to original sources

[Electron microscopic study of isolated proteoglycans].

Chemically isolated separate preparations of the non-aggregating protein-chondroitin-keratin sulphate (PCKS) fraction from the hyaline cartilage and hyaluronic acid (HUA) of the vitreous body and of the umbilicus were investigated by electron microscopy. PCKS and HUA in films without cytochrome c were present in the form of granules and differed by structural organization. The proteoglycans of the cytochrome c films were seen as finely-filamentous-cellular network, and were distinctly differentiated by their macromolecular organization. A mixture of both proteoglycans formed complexes as a result of a noncovalent interaction. Uranyl acetate ensured a good contrasting of proteoglycans, especially of PCKS, without cytochrome c.

Acetates↗

Ultrastructure of melanocytes and premelanosomes in the human epidermis during melanogenesis.

Two types of melanocytes differing in their ultrastructural organization--active and "spent," or reserve--are present in the adult human epidermis. In active melanocytes, intensive melanogenesis takes place, and six stages of melanosomes development can be distinguished in them. The "spent" melanocytes do not contain premelanosomes, and the presence of glycogen inside and around them is evidently indicative of a phase preceding restoration of their function.

Adult↗