Biomedical subjects
Publications and source records attributed to I N Okeke.
It is sometimes desirable to demonstrate bacterial capsules during the routine examination of clinical isolates. Apart from the Indian ink method, methods of demonstrating bacterial capsules are not only tedious but are often non-reproducible. A combined positive-negative capsule staining procedure which is simple, rapid and reproducible is described.
In developing countries, acquired bacterial resistance to antimicrobial agents is common in isolates from healthy persons and from persons with community-acquired infections. Complex socioeconomic and behavioral factors associated with antibiotic resistance, particularly regarding diarrheal and respiratory pathogens, in developing tropical countries, include misuse of antibiotics by health professionals, unskilled practitioners, and laypersons; poor drug quality; unhygienic conditions accounting for spread of resistant bacteria; and inadequate surveillance.