[Preventing locomotory diseases caused by static, dynamic load on hands and by local vibration].
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Biomedical subjects
Publications and source records attributed to I N Ushkova.
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The authors necessitate improvement of "Sanitary regulations and rules for lasers design and use" register No. 5804-91. Laser energy could be used as a prophylactic measure in occupational pathology.
Work associated with visual strain results in visual fatigue. Laser radiation in red part of spectrum relieves visual fatigue, activating reduction-oxidation thiol disulfide system in eyes.
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The article presents principles of a universal theory of hygienic regulation, proves a principle of regulation warranty. Maximal allowable level of laser irradiation (wavelength 0.63 and 10.6 mic) was subjected to feedback test, i.e. health state of the examinees was evaluated after the norm setting. The test proved that the Maximal Allowable Level for laser irradiation needs adjustment.
Analysis of literature and the authors' own data suggest that laser-induced occupational disease may be diagnosed in following disorders on the part of: vision--deterioration of light and colour perception, pain and feeling of burning in the eyes; central nervous system--vegetative dysfunction, hypo- or hypertonic neuro-asthenic syndrome manifesting in weakness and fatiguability; cardiovascular system--cardialgias, hypo- or hypertonic neurocirculatory dystonia, hypertonic disease, general weakness, headache; blood--reticulocytosis; enzymes--increase of base phosphatase activity in blood. The whole complex of aforementioned disorders is quite rate (1.5-2% of cases). As a rule, only some of them are evident while sight disorders, vegetative dysfunction and increased activity of base phosphatase predominate.
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In the dynamics of a chronic experiment and after it, the state of the cornea and blood circulation in the uveal tract were investigated, along with the morphological studies of the occipital areas of the brain (area 17) and calculations of the thermal processes in the cornea tissues. Results of the complex studies confirmed that opacification of the cornea was not induced by the damaging heat effect of the CO2-laser irradiation with the energy of illumination at 4.2 x 10(-2) Wt.cm-2 in 120 day-long period.
The status of the microcirculatory skin channel under laser irradiation with wave length 10.6 mkm of different energetic exposures has been studied. Higher density of vessels per unit of area, longer diameter of the vessels, disturbances in the blood flow have been observed in the dynamics of exposure, which can be used as a criterion of harmful skin effect of irradiation.
Local and general reactions have been studied after subjecting a rabbit eye to dispersed helium-neon laser radiation, 8 x 10(-6) wt/cm-2, 10 min daily for 10 days. There were recorded increase of blood filling of the uveal tract of the eye, changes in the indices of systemic hemodynamics, systolic and diastolic pressure, stroke and minute volume of blood volume, activation of separate links of antioxidant system connected both with oxidation-reduction of thiol disulfide system and the functioning of antiperoxide enzymes. The activation of antioxidant system has a local character, the changes in the retina of the eye and pigmented epithelium is expressed stronger than in the peripheral blood. The results obtained speak about relationship between the stimulating effect of helium-neon laser radiation on the rabbit eye and activation of antioxidant system.
The study was undertaken to analyze the state of visual, cardiovascular and antioxidant systems along with peripheral blood exposed to laser emission with the wavelength of 10.6 mm and energetic exposure equal to that of threshold (21 J.cm2) and subthreshold (1/7 of the threshold value). Not only local but also general changes were detected. The cardiovascular and antioxidant systems were most sensitive to this type of exposure. The degree of changes was dose-dependent.
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