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Biomedical subjects

I N Zal'tsman

Publications and source records attributed to I N Zal'tsman.

At least 19 recordsLinked to original sources

[X-ray morphologic characteristics of microcalcination in benign processes and cancer of the breast].

Mammographic and morphologic examination was carried out in 136 females bearing microcalcinates in breast tissue. Morphologic examination identified benign tumors (mostly fibrous cysts) in 72.1% and cancer (mostly ductal and lobular carcinoma in situ or initial signs of invasion) in 27.9% of cases. Calcinates occurred mainly in the epithelium and incipient cancer complexes. The analysis of the data showed shape, structure and distinctness of contours of calcinates to be instrumental in differentiating between malignant and benign lesions.

Adenofibroma↗

[Small focal lesions of the breast: a clinico-morphological analysis].

Morphological and mammographic study of small (less than 1 cm) focal mammary gland lesions of 170 women revealed foci of typical epithelium proliferation of the ducts and lobules, fibrosing adenosis, small duct papillomas and fibroadenoma, intraductal and ductal carcinoma in situ, sometimes with small invasion foci, infiltrating carcinoma, infiltrating lobular carcinoma. Peculiarities of small focal lesion morphology determine the mammographic picture. Analysis of nodular shadows on the mammogram gives as a rule a possibility to differentiate between benign conditions (focal proliferation of the epithelium, fibroadenoma), early carcinoma (intraductal and lobular in situ, sometimes with small foci of invasion) and infiltrating carcinoma. Calcareous deposits in both benign lesions and carcinomas do not differ mammographically. Morphogenetic link was revealed between foci of epithelium proliferation (benign displasia), intraductal and lobular carcinoma in situ and infiltrating carcinoma. Among 65 cases of non-palpable carcinoma, 31 (47.7%) were classified as early carcinoma and 34 (52.3%) as infiltrating carcinoma with a relatively low histological degree of malignancy. In both groups a good postoperative survival was observed.

Adenofibroma↗

[Diagnosis and treatment of nonpalpable breast tumors].

191 patients with nonpalpable breast tumors were admitted to the Clinic of Surgery of the I. M. Sechenov 1st Medical Institute. The tumors were detected during a mass screening survey; none of the patients had any complaints. Examination and palpation failed to detect any pathologic changes in 60.2% of females, while in 39.8%, bilateral mastopathia cystica was found. All patients underwent sectoral resection with interstitial marking of tumor. The marking procedure is described. Morphological examination confirmed X-ray diagnosis in 83% of cases. Most tumors were localized, while incipient invasive features were revealed in 58.3%. Morphologically, such tumors may be considered early cancer. When diagnosis of malignant tumor was confirmed by histological examination, radical mastectomy after the method of Patey was performed (68.9%). The end results of treatment are presented. Early diagnosis and effective therapy of breast cancer are determined by cooperation of X-ray, surgery and pathology department staff.

Adenofibroma↗

[Mass fluorographic studies and their role in detecting breast cancer].

The authors report their experience with the organization of mass fluorographic surveys of breast cancer conducted in the complex with check fluorography of the chest. The results of clinico-roentgenological investigations in 856 females, chosen with a suspicion to focal process in the mammary gland, among 17,000 females subjected to large film fluorgraphy are reported. Per each 1000 investigations there were revealed 22 cases of cancer and 8.1 cases of benign tumors and cysts of the mammary gland. Mass fluorographic survey for breast cancer is an efficient method of recognizing tumors of this localization.

Breast Diseases↗