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Biomedical subjects

I Neu

Publications and source records attributed to I Neu.

At least 37 records · Page 2Linked to original sources
PubMed1981

[Liver biopsy findings in neurologic diseases with special reference to multiple sclerosis].

The histological results of 112 blind liver biopsies in eight etiologically different neurological diseases are reported in which there was no clinically obvious reason for suspecting a liver disease. An unexpectedly high level of morphological liver changes were found in primary diseases of the central nervous system on one hand, which, on the other showed no specificity for a particular neurological disease group. A direct conclusion on the genesis of the individual neurological disease is, however, not possible from the histopathological picture. If one compares the results of the multiple sclerosis patients with these of patients with other neurological diseases there is a great similarity with the myatrophic lateral sclerosis but also with the infectious diseases of the central nervous system.

Alcoholism↗
PubMed1981

[Encephalitis].

Explore the source record for details and available documents.

Adolescent↗
PubMed1980

[Headache associated with underlying internal diseases].

The vascular system of the head is of great importance in most types of headache because of the sympathetic efferents supplying the vessels. From neuroanatomic data it is to be assumed that vascular diseases of different genesis and cardiovascular diseases may give rise to headaches. The connection between headache and hypertensin is discussed at length with reference to pathophysiology. Further, headache is presented as a symptom with reference to observations of our own cases of inflammatory diseases of the vessels, sinus thrombosis, vessel deformities, accidents in anticoagulant therapy with subdural and intraspinal haemorrhages, cerebrospinal lues and endocrinopathies. Tables and illustrations supplement the text.

Aortic Valve Stenosis↗
PubMed1980

[Neurological symptoms in poisoning].

Acute and chronic intoxications become manifest in primary neurological symptoms. After a definition of poisoning the autonomic, neurological and psychological disturbances are briefly discussed and the therapeutic measures presented in a table. Later, the neurological symptoms are described with reference to oberservations of cases of lead, thallium, E 605 (parathion), carbon monoxide, mercury, amphetamine and botulin poisoning. Four table and 9 figures supplement the text.

Adult↗
PubMed1980

[Diagnosis and therapy of multiple sclerosis].

The diagnosis of multiple sclerosis is still a clinical one, and depends on the occurrence of neurological symptoms due to lesions at two or more necessarily distinct sites in the white matter of the central nervous system. Up to now there exists no specific laboratory test for the diagnosis of multiple sclerosis. The cerebrospinal fluid-profile strongly supporting the diagnosis of multiple sclerosis consists of: cell count slightly elevated, total protein concentration normal or slightly elevated, in the electrophoresis distinct immunreaction without disturbance of the blood-brain-barrier, i.e. significant increase of gammaglobulins and IgG, oligoclonal pattern of the gammaglobulin subfractions. Newly developed diagnosistic possibilities are based on the determination of myelin basic protein, determination of the different glycerophosphatides and on the measurement of the activity of lipid hydrolyzing enzymes. Disturbances of lipid metabolism play an important role in the course of demyelination. Therapy of multiple sclerosis by steroids and immunsuppression will be discussed.

Adrenal Cortex Hormones↗
PubMed1980

[Side effects of long-term drug therapy in neurology (author's transl)].

In default of a causal treatment, longterm drug therapy is essential in numerous neurological diseases. For forensic reasons alone, therefore, side effects and interactions typical for the drugs must be taken into consideration. An attempt has been made to review the most important disturbances of longterm treatment with the drugs which are often used in neurology. At the same time the versatile chemotherapeutic substances also used in other special disciplines and which can sometimes produce serious neurological symptoms are also discussed.

Adrenal Cortex Hormones↗
PubMed1980

[Therapeutic value of immunoglobulins in central nervous system infections].

From 218 patients aged 15 to 72 years suffering from inflammatory infectious diseases of the central nervous system, 162 patients were treated with high doses of immunoglobulins (Ig). The therapeutic results were compared with those of the 56 patients without an additive therapy, separately for bacterial and viral infections. If we compare recoveries and deaths or survivals but defective recoveries, the chi-square test reveals that treatment with Ig at the 0.1 percent level is superior to treatment without Ig in a highly significant manner in favor of the use of Ig. Using other criteria, such as the duration of fever and the length of hospital confinement, calculations using Student's t-test also show significant results in favor of Ig. Early beginning of therapy with high doses of Ig given intravenously, or if necessary intrathecally, proved to be of great therapeutic value in lowering the number of fatalities and defective recoveries.

Adolescent↗
PubMed1980

[The intensive treatment of apoplexy (author's transl)].

Up to one third of patients in neurological clinics suffer from cardiovascular diseases. The brain being particularly prone to disturbances, first priority goes to emergency measures taken by the doctor who initially treats the case and to the subsequent treatment in a wellequipped intensive ward in order to reduce to a minimum the residual loss of brain function. A neurological intensive ward offers, in addition to the basic installations for the conservative disciplines, variable equipment including mechanical respirators, and mobile neurophysiological investigation instruments. Drug medication prevalently consists of volume controlled infusions with plasma expanders and circulatory regulation. Alternatives are discussed. Rehabilitation and physiotherapy are essential from the beginning.

Arrhythmias, Cardiac↗
PubMed1979

[Early symptoms and diagnosis of multiple sclerosis].

Multiple Sclerosis is one of the most common neurological diseases in North and Central Europe and USA, the prevalence is 0,03-0,06%. The precise aetiological and pathological processes underlying the disease are still unknown. As there is as yet no laboratory test that is specific for Multiple Sclerosis, the diagnosis is still a clinical one. It depends on the history--a majority of patients has a history of remissions--and on the demonstration of objective signs of lesions in the white matter of the central nervous system. There can be found some early symptoms--such as optic neuritis--and some typical combinations of symptoms that make the diagnosis Multiple Sclerosis probable or clinically definit. Among the laboratory tests the investigation of cerebrospinal fluid is most important.

Adult↗
PubMed1978

[Endogenous cortisol levels after intrathecal injection of triamicinolone acetonide in patients with neurological disease (author's transl)].

A single dose of 40 mg triamcinolone acetonide was injected intrathecally in 30 patients with multiple sclerosis and 20 with other neurological diseases. In 15 of them the endogenous cortisol level was determined on three successive days and their cerebrospinal fluid examined before the triamcinolone injection was given. Cortisol levels were then measured serially for another 15 days after the injection. Contrary to the response after intramuscular injection, the endogenous secretion of cortisol was not significantly depressed after intrathecal administration. The latter is, therefore, suggested in the treatment of inflammatory diseases of the central nervous system and its integuments, and for acute exacerbations of multiple sclerosis.

Humans↗