Biomedical subjects

I Niculescu

Publications and source records attributed to I Niculescu.

32 records · Page 2Linked to original sources

PubMedDate not supplied

Importance of associated viral and bacterial infections in the production of acute pneumonias.

Bacteriologic and virologic investigations carried out in a group of 85 patients with acute pneumonia have allowed the determination of the etiologic agent in 52.9% of the cases. Of these, 40% showed combined viral and bacterial infections. Mixovirus infections were frequently associated with staphylococcic ones (7 out of 8 cases) and adenovirus infections with the pneumococcic ones (6 out of 7 cases). The most severe and longdrawn clinical pictures with frequent pleuropulmonary complications (in 22.24% of the cases) had a biphasic evolution in only 6 of the 18 pneumonias of mixed etiology. For their high frequency and their clinical peculiarities, mixed etiology pneumonias might be considered as distinct clinical entities.

Acute Disease↗

PubMedDate not supplied

The role of some viruses in acute pneumonias in adults.

Virological and bacteriological investigations were performed in 85 patients with acute pneumonias and virus isolation or serological evidence of virus infection were obtained in 37.6% of the cases. Influenza A2 and B viruses were incriminated in 14.1% of the patients; parainfluenza viruses in 7% and adenoviruses in 17.2% of the cases. Coxsackie virus was isolated from one patient's blood, and poliovirus 3 was recovered in 3 cases. In 5 cases associated virus infections were detected.

Adenoviridae↗

PubMedDate not supplied

[Biliodigestive anastomoses; a modality for resolving mechanical jaundice].

Over a period of 14 years a total of 1,996 surgical procedures have been performed on extrahepatic biliary pathways. In 182 cases (9.11%) biliodigestive anastomoses have been done for a therapeutical solution of mechanical jaundice. Biliodigestive anastomoses have been mandatory in 76 cases (41.76%) because of mechanical jaundice induced by biliary stones. In 106 cases the anastomosis was carried out in an attempt to solve mechanical jaundice that was not induced by biliary stones but by other causes. In 45 cases the lesions that had determined the jaundice were benign, and in 61 of the cases malignancy was at the origin of the jaundice. The following types of anastomosis were employed: choledochoduodenal anastomoses were done in 120 cases (65.93%); hepatic duct-duodenal anastomoses in 15 cases (19.23%); hepatojejunal anastomoses in 7 cases (3.84%); recalibration of previous anastomoses in 5 cases (2.74%). These surgical methods, applied in cases of various etiologies, most of them quite severe, in debilitated patients, with iterative surgery, were associated with early postoperative mortality of 8% (13 cases), and a general morbidity of 35% (65 cases), which included: fistulae, anastomotic stenoses, acute postoperative pancreatitis, angiocholitis and suppuration. The late results were good, depending on the etiology of the mechanical jaundice. The authors preferred choledochoduodenal anastomosis for benign lesions, and anastomoses with the diverticular apparatus, or the main biliary pathway in palliative surgery.

Aged↗

PubMedDate not supplied

[Comparative clinico-evolutive and therapeutic aspects in cancer of the right and left colon].

The paper reports on the casuistics of the colon cancer in the Clinic of Surgery of the "Griviţa" Clinical Hospital, for 21 years (1966-1986) with emphasis on the situs peculiarities on the right and left colon. Whereas the left colon cancer (LCC) started in 32% of cases with subocclusive and occlusive syndromes having special implications on the treatment and prognosis, in the right colon cancer (RCC) only in 3.5% of cases the diagnosis was established in the stage of subocclusive syndrome. During surgery the metastatic adenopathy was met in 57% in LCC and only in 37% in RCC, and the hepatic metastases in 17.7% in LCC and in 10.9% in the RCC cases. The immediate postsurgery mortality was present in 12% of the LCC cases and in only 9.3% of the RCC cases. In the last 10 years of the period studied, the patients were periodically readmitted into the hospital, reinvestigated, and monochemotherapy with 5-fluorouracil was applied in sequential cures. In this last period, the survival at 5 years was of 25 (45.4%) in the 55 patients operated for RCC and of 41 (37.6%) in the 109 patients operated for LCC.

Aged↗

PubMedDate not supplied