Biomedical subjects
Publications and source records attributed to I Nonchev.
Ninety four patients with thyrotoxicosis were examined as well as 40 healthy subjects. Normal concentration of sodium, negligible chloride increase and slightly decreased potassium were established in serum. Hematocrite drops in parallel with disease severity. The average erythrocyte volume is increased whereas the average hemoglobin concentration is decreased.
Gastric secretion was investigated in 26 patients, mainly with mature age diabetes and mixed type after a maximal stimulation with pentagastrin (6 microgram/kg). No significant difference was established as compared with the healthy subjects. Hypo- and achlorhydria were found in 19.2 per cent of the patients and hyperchlorhydria in 15.4 per cent. Diabetes duration over 5 years, hyperglycemia over 200 mg%, late degenerative syndrome and insulin treatment reduce significantly the majority of the indices of gastric secretion.