Biomedical subjects

I O Thompson

Publications and source records attributed to I O Thompson.

27 records · Page 2Linked to original sources

PubMed1994

An unusual variant of keratoameloblastoma.

An unusual case of ameloblastoma which depicts cystic follicles containing orthokeratin, parakeratin, desquamated epithelium and necrotic material with dystrophic calcification is presented. The presence of ameloblast-like cells confirms the diagnosis of an ameloblastoma. However, certain features resembled those of the keratoameloblastoma and others, less convincively, the papilliferous keratoameloblastoma. The extensive keratinisation in this tumour and in the aforementioned neoplasms raises the question whether they represent variants of the acanthomatous ameloblastoma.

Adult↗

PubMed1994

A bitemark case with a twist.

This is a case report in which the bite patterns of two suspects were compared to a bitemark on the breast of a murder victim. Each suspect had sufficient concordant features to have been found guilty of producing the bitemark. The irony in this case is that the bitemark was not inflicted by the murderer.

Bites, Human↗

PubMed1993

Oral carriage of Candida in healthy and HIV-seropositive persons.

The prevalence of oral colonization with Candida species was studied in 28 HIV-seropositive and 28 healthy persons. Candida was cultured from 75% and 68% of HIV-positive and control persons, respectively, with a significantly higher density carriage in the HIV-seropositive group. Positive smears were seen in 39% of all patients. Candida albicans was the most frequently isolated species with Biotype 1 accounting for 56% of the isolates. Resistance to antifungal agents was seen in Candida strains isolated from both groups.

AIDS-Related Opportunistic Infections↗

PubMed1993

Recurrent unicystic ameloblastoma of the maxilla.

A previously reported unicystic ameloblastoma, showing luminal plexiform epithelial proliferation and the presence of small islands of odontogenic epithelium in the connective tissue of the cyst wall, recurred 5 years after conservative surgery. The tumour was nucleated and since the epithelial islands were confined to its fibrous capsule a conservative approach was regarded as adequate. In view of the later experience it is now proposed that where cystic ameloblastomas depict epithelial infiltration into the capsule a second excision be considered and that such surgical material be thoroughly examined for signs of epithelial infiltration. Whatever type of treatment the surgeon decides to perform, it is essential to have a long postoperative period of monitoring. Because the presence of islands of odontogenic epithelium in the cyst wall influences the surgical approach, it is recommended that pathologists carefully examine cystic ameloblastoma surgical specimens for their presence. Multiple, even serial sections are required for such examinations. The pathology report should include a description of the islands with an indication of their site in the capsule of the tumour.

Adult↗

PubMed1992

A model for epithelial growth and epithelium-connective tissue interaction studies.

The aim of this study was to evaluate implanted ectocervical biopsy material as a model for morphological studies of normal and abnormal epithelial growth and epithelial-connective tissue interactions. Forty-five specimens were implanted in the flanks of nude (immunodeficient) mice and harvested at 1, 2, 3 and 6 weeks. Superficial necrosis of the epithelial layer with retention of parts of the basal cell layer were evident at 1 and 2 weeks. At 2 weeks granulation tissue enclosed the bases of the implants. Regrowth of epithelium on the surfaces and from the edges of the specimens was seen at 3 weeks. At 6 weeks the specimens were revascularized and the majority coated with a well developed unkeratinized stratified squamous epithelial layer resembling the epithelium of the ectocervix. It is concluded that specimens of human ectocervix, implanted in nude mice, offer the possibility for morphological studies of normal and abnormal epithelial growth and, if experimental difficulties can be overcome, of the epithelial-connective tissue interactions.

Animals↗

PubMed1992

Exhumation following incorrect identification. A case report.

The exhumation of two victims of a light aircraft accident was performed in February 1991 at Oudtshoorn, Cape. The exhumation was ordered by the magistrate on request of the parents of one of the victims who suspected that their son had been wrongly identified at the postmortem examination. At the pre-burial autopsy all the victims were positively identified, but the identity of two of the victims was subsequently reconsidered and reversed because one of them wore a silver bracelet. Burial then took place. The exhumation was ordered one month after the accident at which stage the bodies were in an advanced state of decomposition. Oral autopsies were performed on each of the victims, the jaws were radiographed and postmortem dental records drawn up. Dental records were obtained from the dentists who treated them and the information from these records was used to draw up ante-mortem dental records. A comparison between the postmortem and ante-mortem records showed that the victims were incorrectly identified and reburial in the correct graves was subsquently carried out. This case again emphasies the importance of dental identification in cases of severe burning, multilation or decomposition in order to avoid mistaken identity and incorrect burial in the future.

Accidents, Aviation↗

PubMed1992

Metastatic squamous carcinoma manifesting as a periapical lesion.

Periapical pathoses which often appear as vague radiolucent areas on routine roentgenographs, are treated by endodontic therapy alone or followed by apicoectomy. Clinicians as well as histopathologists should be aware that a metastatic carcinoma to the jaws can mimic apical lesions. A case of metastatic carcinoma from the larynx, which manifested as a periapical lesion with the clinical signs and symptoms of pulpal pathology, is described.

Adult↗

PubMed1990

Odontoameloblastoma: a case report.

Confusion in the early literature regarding the odontoameloblastoma, resulted in this tumour being reported under a variety of names. Many of the reported cases fail to meet the clinical and histological criteria required for classification as odontoameloblastomata. This article attempts to present a case with clinical, radiological and histological features that meet the required criteria. In this case the ameloblastic component intermingled with the dental hard tissues.

Adult↗

PubMed1986

A unicystic ameloblastoma mimicking a 'globulo-maxillary' cyst: a case report.

A rare case of unicystic ameloblastoma is reported, which clinically mimicked a 'globulo-maxillary' cyst. The cyst wall was lined by stratified squamous epithelium with scattered mucous cells. In one area a nodule of ameloblastic proliferation was present. The lesion was removed conservatively and there were no signs of recurrence after a 2-year follow-up period.

Adult↗