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I Obando Santaella

Publications and source records attributed to I Obando Santaella.

13 recordsLinked to original sources
PubMed2000

[Meningitis due to haemophilus influenzae type f].

We report an immunocompetent 5-month-old boy with Haemophilus influenzae type f (Hif) meningitis. The patient had previously been immunized with two doses of Hib conjugate vaccine (PRP-T). Vaccination failure was initially suspected based on Gram stain report. The results of culture identified a non-b Haemophilus influenzae capsular serotype (Hif).Non-Hib serotypes should be considered as potential pathogenic agents in children under the age of 5 years with invasive diseases. An adequate epidemiological surveillance system would be helpful in detecting the role of these non-b Hif serotypes as significant pathogens, which appear to be on the increase.

Haemophilus influenzae↗
PubMed1990

[Homozygous familial hypercholesterolemia. Response to combined cholestyramine and lovastatin therapy].

Homozygous familiar hypercholesterolemia (FH) is a serious inherited disease caused by a genetic defect in the cell surface receptor that controls the degradation of low density lipoprotein (LDL). These patients often have myocardial infarction in their teens or early adulthood and are usually unresponsive to drugs. Recently it has been reported promising results using combined drugs regimens in patients with residual receptor activity. We report a new additional patient with receptor-defective homozygous FH treated with a combination of lovastatin and cholestyramine. The cholesterol levels were reduced in a 67% and there were adverse events related to treatment during a 7 month period of follow-up.

Child, Preschool↗
PubMedDate not supplied

[IgG2 deficiency. Its clinical correlation with recurrent otitis media in childhood].

IgG2 deficiency has been reported in two recent years as an antibody deficiency associated mainly with recurrent acute and chronic ORL and lower respiratory and recurrent otitis media in children evaluated. We discuss the most rational approach to the treatment with special reference to the replacement therapy with intravenous immunoglobulin.

Child, Preschool↗