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Biomedical subjects

I Oepen

Publications and source records attributed to I Oepen.

At least 37 records · Page 2Linked to original sources
PubMed1980

[On the definition of "practising in accordance with the prerequisites laid down in the 'Heilpraktiker' law". Inadequacies of the law and judicature (author's transl)].

The case of a "smoking disaccustomer" and "psycholigist" is reported who carried out his profitable job at various places. Aided by his lawyer, he successfully resisted all attempts by the authorities to acquire registration as a lay healer. In this way, he skillfully took advantage of the existing loopholes of legislation and even went as far as threaten the authorities. Finally, his dealings were brought to an end by the district court of Kassel on March 21, 1978, which ruled that the "Heilpraktiker" law ought to protect the people against mistreatment and exploitation. Thus criteria of the German "Reichsversicherungsordnung" are not applicable in this case.

Germany, West↗
PubMed1980

[Typing of gonadospecific diaphorase (DIA3) in seminal stains and esterase D typing in seminal and saliva stains (author's transl)].

1. The gonadospecific DIA3 types were traceable for 4 weeks, in some cases for 6 weeks. 2. EsD polymorphism was not demonstrable by starch gel electrophoresis in sperm, not even in sperm lysates. 3. EsA patterns showed only non-reproducible differences. 4. Because of their low concentrations, salivary esterase cannot cause errors when mixed stains are examined.

Electrophoresis, Starch Gel↗
PubMed1980

[On the ABO character of human hair (author's transl)].

Typing results of 346 hair samples from 195 donors by a modification of the absorption-elution test are reported. Antihuman globulin serum was added at the end of the usual procedure. In this way, agglutinations increased in strength, while negative reactions were not influenced. In the coure of this investigation, other steps of the method were modified tentatively. The least erros were noted by analysing hairs from the neck (instead of the crown region), by the use of high-titered anti-A, B(O) serum and of unwashed red-cell suspensions, by addition of undiluted Coombs serum and reading of the results after 24h. Nevertheless, the rate of errors remained at 20% which is still too much. Also, a systematic and reproducible error may occur which causes results differing from the red-cell type and is comparable to the phenomenon of aberrant secretors.

ABO Blood-Group System↗
PubMed1980

[On cytotherapy and cytotherapeutists (author's transl)].

Arguments used by advocates and opponents of Cytotherapy, supported by numerous quotations are set against each other. Any agreement is made rather difficult by attitudes of Cytotherapeutists which are characterized by pseudoscientific reasoning. Coarse examples of this particular way of arguing are given. Furthermore, indication inventories appear vastly exaggerated, documentation is incomplete, judgment of alleged successes and incidents are highly disputable, and angry reactions against learned critics were published. Since alleged successes could not be proved on examination, and because of lack of any scientific proof of efficiency, the warning of the Scientific Advisory Board of the German Federal Arztekammer issued in 1976 must be considered as well-founded. The same goes for the 1972 Federal Social Court's ruling which excludes any reward by social health insurance bodies of expenses incurred by Cytotherapy.

Animals↗
PubMed1977

[On the suitability of spectrophotometric analyses for the estimation of blood stain age (author's transl)].

The spectrophotometric methods of Kind et al. and Kleihauer et al. were checked by more than 900 experiments on 85 blood stains on different material (cotton, nyltest and paper) from native and citrate blood, aged at room temperature up to 5 years. As a result, the variation of values within one age-group exceeded the differences between the values of samples of different age. Therefore, both methods are thought to be unsuitable for the estimation of blood stain age in practical forensic medicine, although the general trend described by the above authors could be confirmed.

Blood Stains↗
PubMed1977

[Determination of alpha1-fetoprotein in bloodstains by means of electrophoresis on cellulose acete (author's transl)].

The distinction of foetal from adult blood stains prepared from 219 cord blood samples was possible, without exception, up to eight months by means of alpha1-fetoprotein precipitation, carried out by immuno-electrophoresis on cellulose acetate (Biotest) instead of agar gel, as described by Patzelt, Geserick and Lignitz. The material carrying the blood stains (glass, wood, paper and linen) did not influence the results.

Blood Stains↗
PubMed1977

[A photometric method for the diagnosis of pregnancy in blood stains by determination of heat-stable alkaline phosphatase (EC 3.1.3.1). A modification of Oya, Asano and Fuwa's technique (author's transl)].

A quantitative method, described by Oya and coworkers was modified. In this way, venous blood from pregnant and nonpregnant women in blood stains can be reliably differentiated up to at least 19 months storage although as a qualitative test only. 1--3 cm2 of cloth stained with blood is needed and even less from placental blood stains.

Alkalies↗
PubMed1977

[Determination of the factors Gm(1,2,4,5,21) and Inv(1) in human secretions: saliva, sweat, nasal secretion and semen (author's transl)].

If there is enough stain material available Gm and InV factors can be proved to be present in semen. Contamination by nasal or vaginal secretions should be taken into account. Sweat, however, does not interfere with the determination. In saliva, InV but no Gm properties were demonstrable. Stamp glue reacts unspecifically with InV antiserum and could therefore be a source of error. The conclusive value of Gm and InV findings as evidence in court was derived from the phenotype frequencies obtained in blood samples of 400 unrelated persons.

Antibody Formation↗
PubMed1976

[Polymorphism in alkaline phosphatase (author's transl)].

1. In horizontal starch-gel electrophoresis placental extracts show an alkaline phosphatase polymorphism which - according to ROBSON and HARRIS - depends on the fetal genotype. Investigations carried out with a series of 73 placentas revealed 5 of the common 6 phenotypes. Their frequencies were in good accordance with the figures published by the English authors. However, there had been difficulties in typing because of obscrue realizing of the patterns. 2. Although there exists a polymorphism of the heart-stable alkaline phosphatase as observed in 66 serum samples from women at delivery, only four types could be distinguished which, however, could not be related to the placental patterns with any certainty. 3. In all but one of 66 samples of cord serum, investigated simultaneously, a single band only could be observed moving at a slower speed than the serum bands of adult pregnant and non-pregnant persons. This is in conformity with the results of the other investigators. 4. In 18 samples of unheated serum the amount of heat-labile alkaline phosphatase was unimportant and did not alter the features of the heat-stable portion of the enzyme. 5. Contrary to expectations, the alkaline phosphatase polymorphism has no medicolegal relevance.

Alkaline Phosphatase↗