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Biomedical subjects

I Olitzky

Publications and source records attributed to I Olitzky.

5 recordsLinked to original sources
PubMed1972

Automated complement fixation with low reagent consumption.

A microvolume automated (continuous-flow) system for the detection of complement-fixing antigen or antibody was evaluated. The model complement fixation test used was the detection of deoxyribonucleic acid antibody, and comparisons were made with a manual procedure. An "automatic two-dilution" feature of the apparatus was not used because of the clinical need for antibody titers. The system proved useful for the detection and estimation of anti-deoxyribonucleic acid antibody in patients with systemic lupus erythematosus and, indeed, accomplished this with low reagent consumption, a useful feature not available in "older" continuous-flow complement fixation systems.

Animals↗
PubMed1968

Standardized, automated procedure for measurement of serum hemolytic complement activity.

In the interest of standardizing and automating complement fixation procedures, an AutoAnalyzer manifold was designed in which the reagents are mixed in proportions similar to that of the Laboratory Branch Complement Fixation test. By bypassing the fixation stage, the manifold proved useful for measuring serum hemolytic complement activity (C'). As many as 21 serum samples per hour can be screened by testing two appropriate dilutions. Normal adult C' titers measured by the automated procedure ranged from 58 to 103 C'H(50) units per ml.

Adult↗