The present paper reports on 34 cases of meningococcal meningitis admitted during the last three years to the Clinic of Communicable Diseases of Cluj. The incidence was higher in adolescents and young adults (76%). The clinical form was severe in 10 cases, medium in 19 cases and mild in 5 cases. All the patients recovered, with a mean duration of the disease of 9-12 days. No sequelae or relapses were recorded. The treatment was based upon penicillin G, 15 million U/day. In 17 cases sulfonamides were associated and in 5 cases chloramphenicol and ampicillin. In 29 cases intravenous, intramuscular or oral cortisone was administered and in 5 cases intrathecally. The results obtained in the cases treated only with penicillin were identical to those obtained by an associated therapy. Worthy of note was the decrease of the sensitivity of meningococci to sulfonamides and chloramphenicol and their increased resistance to tetracyclin and erythromycin.

Adolescent↗

PubMedDate not supplied

[The disseminated intravascular coagulation syndrome and infection].

The disseminated intravascular coagulation syndrome (1) Definition. History. (2) Etiopathogeny of the disseminated intravascular coagulation syndrome. (3) The clinical and laboratory diagnosis of the disseminated intravascular coagulation syndrome. (4) The principal infections in which the disseminated intravascular coagulation syndrome has been described: bacterial, viral, rickettsial, parasitic, mycotic. (5) Treatment of the disseminated intravascular coagulation syndrome.

Aminocaproates↗

PubMedDate not supplied

[Current aspects of septicemia with gram-negative bacilli].

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Adolescent↗

PubMedDate not supplied

[Incidence of antibodies against hepatitis virus A (anti-HA) in a non-selected urban population].

Anti-HA antibodies were determined by radioimmunoassay according to the HAVAB-ABBOTT technique in 244 subjects, of whom 194 without hepatic involvement, 25 with non B hva and 25 former non B hva patients. Anti-HA anti-bodies were found in 67% of the healthy subjects and 100% of the patients and former hva cases. The incidence of anti-HA antibodies increases with age being in 30% of children and 83.5% of adults. A peak incidence was found between the ages 21 and 30 years. In the district investigated subclinical infection with HVA was frequent, beginning in childhood and up to the age of 30 years. The qualitative HAVAB test is adequate for epidemiological investigations; a quantitative variant is necessary for the diagnosis.

Adolescent↗

PubMedDate not supplied

[Post-transfusion hepatitis].

The incidence, aetiology, evolution, prognosis and treatment of PTH was studied in 253 cases selected from among 7224 patients with acute viral hepatitis, admitted to hospital during the 1973-1979 period. Following the rational application of transfusion and elimination of hepatitis virus B carriers, there was a three-fold decrease in the frequency of PTH. Control of the donors by contra-immunoelectrophoresis showed that PTH type B represents at least 26.8% of the total number of PTH. In order to eliminate PTH type B a more sensitive technique should be used in order to detect HBs Ag in the donors. The treatment being complex and hospitalization prolonged, the cost of PTH patients is greater than that of acute viral hepatitis patients, in general, justifying the additional expenses required for the prevention of PTH.

Adolescent↗

PubMedDate not supplied

[Frequency and prognostic value of the "e" system in hepatitis B virus infections].

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Antibodies, Viral↗

PubMedDate not supplied

[Frequency and prognostic value of the "e" system in hepatitis B virus infection].

The frequency and prognostic value of the "e" system was determined in acute and chronic hepatitis patients and in blood donors by immunodiffusion on Abott rheophoresis plates. The incidence of HBe Ag in acute viral hepatitis was 20% at the beginning of the disease; its persistance indicated a prolonged evolution and a tendency to a chronic course. The presence of anti-HBe at the beginning of the acute disease may indicate the onset of a non-B hepatitis in an HBe carrier. In chronic hepatitis the incidence of HBe Ag was 58% and in blood donors only 6%. Anti-HBe was absent in chronic hepatitis and present in 15% of blood donors.

Hepatitis B↗