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Biomedical subjects

I P Unsworth

Publications and source records attributed to I P Unsworth.

At least 19 recordsLinked to original sources
PubMed1995

Cellulitis owing to Aeromonas hydrophilia: treatment with hyperbaric oxygen.

Aeromonas hydrophilia, a Gram-negative facultative anaerobe, is a rare cause of cellulitis. We review the literature and report a case of Aeromonas hydrophilia cellulitis which failed to respond to the conventional management of surgical debridement and antibiotics. Hyperbaric oxygen therapy was used successfully to control the infection. As far as we are aware this is the first case in world literature of Aeromonas hydrophilia cellulitis treated with hyperbaric oxygen.

Aeromonas hydrophila↗
PubMed1991

Pneumatosis cystoides intestinalis: an experience with hyperbaric oxygen treatment.

Gut wall gas cysts are uncommon and are an occasional cause of abdominal symptoms. Their aetiology is uncertain and both bacterial infection and chronic airways disease are popularly held theories. At Prince Henry Hospital (PHH) between 1980 and 1986, 8 patients with pneumatosis cystoides intestinalis (PCI) underwent 11 courses of hyperbaric oxygen treatment (HBO). This is the largest reported series of HBO treatment of PCI. In April 1990 attempts were made to recall all patients to assess cyst and symptom status. Two had died from unrelated causes; the other six were reviewed--of these, one declined further endoscopy and the other five consented. The 11 courses of treatment all resulted in pronounced symptomatic responses. This was followed by 7 early symptomatic recurrences and 4 long-term cures. These four remain asymptomatic and cyst-free at a minimum of 4 years to a maximum of 9 years follow-up. Of these 4 cures, cyst resolution was documented immediately post-HBO treatment in two and not assessed in two. In the 7 recurrences, failure of cyst resolution was documented immediately post-HBO treatment in six and not assessed in one. Three patients had chronic airways disease, and two of these have complete resolution of PCI. It is concluded that HBO treatment is effective for PCI provided it is continued until cyst resolution has occurred and not just until symptomatic improvement. These observations suggest that PCI is curable and argues against the pulmonary theory of aetiology.

Aged↗
PubMed1984

Gas gangrene. An 11-year review of 73 cases managed with hyperbaric oxygen.

An 11-year review is presented of 73 patients treated for gas gangrene at The Prince Henry Hospital. The geographical collection area extended throughout the States of New South Wales and Queensland and to Papua New Guinea. The commonest aetiological factor was found to be motor-vehicle trauma, motor-cycle accidents producing compound limb fractures in particular. The infecting organisms in these cases were most commonly clostridia. The diagnosis of the disease remains a clinical one. Treatment consisted of three facets: conservative surgery, as much of the limb or viable tissue as possible being preserved; high-dose penicillin administration; and hyperbaric oxygen therapy. Death occurred in 15 cases, gas gangrene being the principal cause in seven. However the incidence of gas gangrene has diminished since 1971, and there are hopes that it will decrease further through adequate prophylaxis and prevention in civilian surgical practice.

Accidents, Traffic↗
PubMed1978

Hyperbaric oxygen and acute spinal cord injuries in humans.

Clinical assessment of a regime of hyperbaric oxygen within 12 hours of acute spinal injury in humans suggests that further study of this method of treatment is indicated. For statistical proof of the efficacy of this form of treatment study of a large number of patients is necessary and an Australia-wide study is suggested. A recommendation is made for early referral to the spinal unit.

Adult↗
PubMed1978

No ignition risk with hyperbaric enflurane.

A series of experiments was undertaken with Enflurane under hyperbaric conditions to determine whether or not it was explosive under these conditions. No risk of detonation was shown with concentrations of Enflurane up to 5% in either oxygen or nitrous oxide mixtures under conditions of hyperbaria to 3 A.T.A. (Atmospheres Absolute).

Anesthesia, Inhalation↗
PubMed1973

Gas gangrene.

Explore the source record for details and available documents.

Antitoxins↗