[The problem of medical research in Croatia].
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Biomedical subjects
Publications and source records attributed to I Padovan.
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The program of the electronystagmographic examinations in the pathology of the central nervous system contains 11 groups of tasks. Sixty signs of central impairments are listed, from which 26 nystagmic irregularities had a small diagnostic value. No sign occuring alone could be taken as pathognomonic, only a group of signs can be used for the impairment localization. Besides for the peripheral vestibular and the peripheral vestibulocochlear impairments, the authors succeeded to make a group containing pathogomonic signs for mixed vestibular impairments as well as for multiple sclerosis affecting vestibular structures.
A vibratory stimulus at a frequency of about 100 Hz was transmitted through a bone conductor on the mastoid in 26 profoundly deaf subjects. In all of them, the function of the vestibular apparatus was tested by means of the Fitzgerald-Hallpike caloric test. In some of the deaf subjects, evoked potentials were recorded, which following the frequency of the stimulus and which according to amplitude and latency characteristics, corresponded to the frequency following response (FFR). A close correlation was found between the normal function of the vestibular apparatus and the appearance of FFR in deaf subjects. The possible receptors of the stimulus and the afferent pathways which generate the recorded response are discussed.
In 12 healthy volunteers, and 5 prelingually and 5 postlingually profoundly deaf subjects, a 500 Hz filtered click stimulus was applied to the mastoid via the bone conductor. In all the healthy volunteers, middle latency response (MLR) was recorded. Among all profoundly deaf subjects, MLR was recorded only in 2 with prelingually deafness; these two subjects were also the only ones with normal vestibular function. The possible mechanisms of the MLR appearance in deaf subjects are discussed.
The fast component of nystagmus begins where the slow component stops, at the point called the threshold of the fast component R. The fast component should last until the eye is brought back into the position of azimuth zero, where the slow component begins anew. This point can be called the threshold of the slow component L. So the fast component has a span from R to L and is presented as a side of a triangle r. An additional corrective procedure in electronystagmography is suggested to avoid failures and to define the true position of L. This is the way to correct the false information on nystagmic elements and to learn the unknown features of the fast component.
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