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Biomedical subjects

I Penev

Publications and source records attributed to I Penev.

At least 19 recordsLinked to original sources

[The diagnosis and complications of pregnancy in uterine malformation].

During the period from January 1985 until May 1990, 56 pregnant women with malformed uterus were observed for the clinical curse of pregnancy: 22 women in the first, 26 in the second and 8 in the third trimester. The diagnosis was made by complex investigations: vaginal examination--in 48 cases, ultrasound examination-in 51 cases, previous hysterosalpingography--in 14 cases. In 17 women the performance of a cerclage was needed. In 17 women a hormonal treatment with gravibinon was applied. The results prove the reliability and validity of ultrasound examination, especially through the second trimester of pregnancy and the need of adequate hormonal (gravibinon) and operative treatment (cerclage).

Combined Modality Therapy↗

[Surgical delivery in multiple pregnancy].

During the period 1986-1990, 142 women with multiple pregnancy were treated with the following methods: normal delivery--104 women (73.2%), sectio caesarea--35 women (24.7%), internal versio--2 women (1.4%), forceps operation--1 woman (0.7%). In 81 cases with premature delivery (before 37 week of gestation) was done: normal delivery--64 women (79%), sectio caesarea--15 women (18.5%), internal versio--2 women (2.5%). n 45 cases with unfavourable positions of foetuses it was performed: normal delivery--18 women (40%), sectio caesarea--25 women (55.6%), internal versio-2 women (4.4). (In 10 cases with sectio caesarea and 2 cases with internal versio the indications were prematurity as well as unfavourable positions of the foetuses). The authors consider that it is necessary to increase the operative interventions (sectio caesarea) in cases of multiple pregnancy.

Apgar Score↗

[The ultrasonic diagnosis of an early abnormal pregnancy].

During the period of January 1993 to February 1994, 70 pregnant women had an ultrasonic diagnosis of abnormal pregnancy. 111 ultrasound examinations were made--mean 1.6 of each woman. The ultrasonic diagnosis up to 70 women was: missed abortion--35 women (50%), blighted ovum--30 women (42.9%), other diagnosis--5 women (7.1%). Histological examination of material was made with 64 women (91.4%). Comparing the ultrasonic diagnosis to histological results, authors do not recommend a final diagnosis before eight gestation week.

Abortion, Missed↗

[The lead concentration of the maternal serum in cases of missed abortion].

The neurotoxic effect of lead is well known, but the investigations of the pregnant women are still few. The aim of the present study is to establish whether there is difference in the concentration of lead in the blood of the pregnant women with missed abortion in comparison with women with normally developing pregnancy in the same gestational age. There were examined 35 patients with missed abortion and a control group of 26 women with normal pregnancy in the same gestational age. There were established statistically significant higher levels of lead (p < 0.001) in women with normal pregnancy (124.46 +/- 46.65 micrograms/l) in comparison with cases with missed abortion (183.73 +/- 24.16 micrograms/l). There were discussed the possible mechanisms, which can be responsible for the observed changes.

Abortion, Missed↗