Clinical governance.
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Financing, Government↗
Biomedical subjects
I R Fletcher
Publications and source records attributed to I R Fletcher.
A new method for securing endotracheal tubes during orthognathic surgery.
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Adhesives↗
Sticky labels to indicate hazard for anaesthesia.
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Anesthesia↗
The effects of calcium-blocking agents on sympathetic responses to acute haemorrhagic shock in dogs.
The effects of three calcium channel-blocking agents, verapamil, nifedipine and diltiazem, given intravenously, have been studied on the cardiovascular and sympathetic responses to acute haemorrhagic shock in anaesthetized dogs. Following acute haemorrhage, cardiac output, mean pulmonary artery pressure, mean right atrial pressure, and pulmonary capillary wedge pressure all fell, and adrenaline, noradrenaline and plasma renin activity rose. In the presence of each calcium antagonist the fall in cardiac output, mean pulmonary artery pressure, central venous pressure and pulmonary capillary wedge pressure was similar, and the rise in catecholamine levels unaffected. The rise in plasma renin activity following diltiazem 0.02 mg kg-1 or 0.1 mg kg-1 or nifedipine 0.01 mg kg-1 was similar to values in a control group, whereas in those receiving verapamil 0.15 mg kg-1 or 0.6 mg kg-1, or nifedipine 0.05 mg kg-1, the rise was greater.
Animals↗
Profile of recovery after general anaesthesia.
The duration of impairment of mental functioning after anaesthesia was studied in 55 patients undergoing hernia repair who were divided into three groups in which the method of induction of anaesthesia (intravenous or inhalational) and ventilation (spontaneous or controlled) was varied. Performance in a five minute serial reaction time test and subjective estimates of coordination were assessed four times a day for two complete postoperative days and were compared with those in a control group of orthopaedic patients in hospital. After considerable impairment initially, reaction times in all groups gradually returned towards control values, but in patients breathing spontaneously during anaesthesia impairment recurred during the second postoperative day. These results suggest that such patients should be advised not to undertake hazardous tasks such as driving a car for at least 48 hours after a general anaesthetic. Discrepancies between subjective and objective assessments of impairment also suggest that patients should not rely on their own assessments of fitness to drive.
Anesthesia, General↗
The MIE Carden ventilator. A description and laboratory assessment.
The Carden ventilator is described and assessed when used in adult and paediatric modes against test lungs with varying compliance and airways resistance. The ventilator proved to have limited ability to compensate for changes in test lung compliance and resistance. Repeated confirmation of tidal volume is mandatory, but the Carden combines simplicity with flexibility of design and may prove useful as a theatre ventilator.
Adult↗
Anaesthesia for carcinoid syndrome.
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Anesthesia, General↗
The Blease 5300 ventilator: an assessment.
The Blease 5300 ventilator is described. A laboratory assessment of its performance gave satisfactory results and confirmed the favourable impressions formed by medical and nursing staff, in the intensive therapy unit during a trial lasting 3 months.
Evaluation Studies as Topic↗