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Biomedical subjects

I R Hill

Publications and source records attributed to I R Hill.

At least 19 recordsLinked to original sources

An analysis of factors impeding passenger escape from aircraft fires.

The aviation world has long recognised that fires in aircraft are potentially very dangerous, being the cause of considerable mortality and morbidity even in otherwise survivable accidents. The evidence accumulated in the British Airtours Boeing 737 accident at Manchester International Airport on 22 August 1985, and the information acquired as a result of this investigation, reinforce the long held view that protection for passengers is needed. Heat, smoke, and toxic fumes can incapacitate people very rapidly. The time it took for people to die cannot be accurately assessed, but it is likely that all died within 4.5 min of the emergency being declared and probably within 2 min of smoke and flames entering the fuselage. Thus, it is obvious that new measures will have to be taken if lives are to be saved in future events of this nature.

Aircraft

Angiographic coronary morphology in postinfarction angina.

To investigate the pathophysiologic relevance of angiographically irregular coronary stenoses in postinfarction angina (PIA), we analyzed the clinical course and coronary angiograms of 73 patients studied within 30 days of infarction. Coronary lesions were classified as smooth or irregular. Thirty-six patients had PIA (Group 1) and 37 had an uncomplicated course (Group 2). Irregular lesion(s) in patent infarct-related arteries were found in 77% of Group 1 vs. 24% of Group 2 patients (P less than 0.005). Irregular lesion(s) in any coronary artery were found in 58% of Group 1 versus 19% of Group 2 patients (P less than 0.002). Other univariate predictors of PIA included older age, hypertension, angina before myocardial infarct, lower peak creatine kinase, three-vessel disease, and higher modified Gensini score. Multivariate analysis ranked lesion irregularity as the strongest predictor of PIA. Our data suggests that ruptured atherosclerotic plaques may be important in the pathogenesis of PIA. It is possible that lesion irregularity is associated with an active process and/or a residual thrombus, which may be responsible for postinfarction angina.

Angina Pectoris

Incapacitation and fires.

Traditionally quoted levels of the products of combustion are too high to account for all the problems of incapacitation and death in fires. Because people may not die instantly in a fire, they can continue to inhale toxic gases after collapse. Collapse may occur very quickly. Experience drawn from analysing the effects of the Manchester Boeing 737 accident and a building fire are used to debate this issue.

Carboxyhemoglobin

Suppurative pericarditis due to Angelchik prosthesis.

Hiatus hernia is a common condition and while medical treatment is often sufficient, in some cases surgery may be necessary. Although there are a number of surgical treatments available, none has been totally successful. We report a case in which use of the Angelchik prosthesis proved fatal.

Aged

Fires.

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Aged

Mechanism of injury in aircraft accidents--a theoretical approach.

The forensic principles for the examination of wounds are well known (1, 15), and many authors have written at length about the way in which injuries can be classified and how this can be related to their cause. Incised wounds inflicted by knives, and stellate, bursting-type injuries due to blunt objects for example, are commonplace in any forensic practice. Thankfully, although there has been a recent upsurge, aircraft accidents are not common, and so it is conceivable that few pathologists will be called upon to investigate them. Nevertheless, because of the diagnostic importance of the findings, in the context of air safety, pathologists should be aware of the major potential findings. The reasons why aircraft accidents are investigated with greater thoroughness than road traffic accidents, for example, are based upon the early recognition of hazards thought to be attributable to flight. Although many of the early fears were based more upon possibilities than on probabilities, they have left us with a legacy of a comprehensive investigating system. This has had, in turn, its effects in improving flight safety. This paper looks at the basis for this, as illustrated by the mechanism of the injury involved.

Accidents, Aviation

The immediate problems of aircraft fires.

Fires that occur either while aircraft are in flight or as a consequence of a crash remain life-threatening possibilities despite progress in technology and adoption of safety precautions. This article details some of the likely causes of aircraft fires, the resulting dangers in the immediate environment, prospects for survival, and recommends additional measures that may help avoid future accidents.

Accidents, Aviation

Toxicological findings in fatal aircraft accidents in the United Kingdom.

Toxicology studies can contribute much to investigations into the causes of accidents. This paper examines toxicological data from 485 fatal aircraft accidents over a 24-year period in terms of relevance to causing accidents and difficulties in procuring samples for analysis.

Accidents, Aviation

Toxocara canis larvae in the brain of a British child.

The clinical and autopsy findings of a two and a half year-old infant with Toxocara sp. infection of the brain and granulomatous lesions in the liver are reported. The cause of death was non-accidental injury. The relationship between Toxocara infection and behavioural disorders is discussed.

Ascariasis