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Biomedical subjects

I R Perry

Publications and source records attributed to I R Perry.

8 recordsLinked to original sources

A new mouthpiece for the Wright peak flow meter.

When tested against artificially produced peak flows, the Wright peak flow meter is found to be an accurate instrument. A factor contributing to the variation seen when the meter is in clinical use in the design of the mouthpiece. This paper reports the results obtained using a new mouthpiece designed specifically to reduce this variation.

Adult

The use of a digital computer for the on-line real-time assessment of neuromuscular blockade in anaesthetized man.

A computer program written mainly in a high level language (ALGOL), but with the sampling routine and certain calculations written in assembly language (SIR), has been developed to assess neuromuscular blockade in anaesthetized man by means of an Elliott 903 digital computer. The program allows the on-line real-time analysis of a range of variables including twitch height, maximum slope of twitch and twitch pulse widths, peak height of tetanic contraction, end-height of tetanic contraction, the tetanic tension ratio and the percentage tetanic transmission. The program has been used to investigate the pattern of action of neuromuscular blocking drugs and has particular value in the study of the pharmacokinetic action of these drugs.

Computers

Computer analysis of electromyographic signals from the human bladder and urethral and anal sphincters.

An investigation has been made into the form of the EMG signals from the human bladder and urethral and anal sphincters. A buildup of the low frequency detrusor EMG before micturition occurs in some patients and this is more marked in patients with urgency. A good correlation occurs between the amount of EMG activity and bladder activity as assessed by the cystometrogram. Marked spike activity has been seen in the detrusor EMGs of patients with irritable bladders. The comparison of anal and urethral sphincter EMGs is of interest from the viewpoint of the anatomy of the urethral sphincter and the mechanism of micturition.

Adolescent