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Biomedical subjects

I Rodríguez López

Publications and source records attributed to I Rodríguez López.

At least 19 recordsLinked to original sources
PubMed2005

[Drug interactions in the prescription of medical patients at hospital discharge].

OBJECTIVES: To detect and evaluate the clinical significance of drugs interactions in patients discharged from hospital. MATERIAL AND METHODS: We retrospectively screened the medication for potential drug interactions of 412 patients discharged. Interactions were catalogued according to clinical importance following the Hansten and Horn's classification. RESULTS: Three hundred twenty-nine potential interactions were detected. The 39.9% of the patients had at least one potentially interacting drug combination. The 52.6% of the interactions were catalogued as Class 3, bearing in mind minimizing the risk of the interaction. We did not find any Class 1 or 2 interactions, which have potentially major severity. Oral anticoagulants and digoxin were the most frequently implicated drugs. The patient monitoring was well done in the 100% of the interactions of Oral anticoagulants with other drug, but in the interactions of digoxin with another, this control was not done adequately. One patient was rehospitalised due to high levels of digoxin, he had been discharged with two potential interactions. CONCLUSIONS: The frequently of potential drug interactions in medical patients at hospital discharged was high, but the clinical significance appear to be low.

Adult↗
PubMed2003

[Endocarditis caused by Stenotrophomonas maltophilia: report of a case and review of literature].

We report a case of a 65 year-old woman with late endocarditis of prosthetic aortic valve and paravalvular abscess by Stenotrophomonas maltophilia, which had an acute presentation for the memtionated abscess broken, with fever, bacteremia and congestive heart failure secondary to severity aortic regurgitation. Itacute;s a rare cause of endocarditis with only 22 cases descripted in medical literature, the most of them in parenteral drug addict and as complication of cardiac valve replacement. The literature is reviewed and relate the epidemiology, clinical and prognosis characteristics of this disease, the same as his treatment and prevention.

Abscess↗
PubMed2002

[Use of beta-blockers for treatment of cardiac failure].

The rationale for betablocker use in heart failure, based on neurohormonal physiology, has been established over the past 20 years. Recent trials have shown the unequivocal benefits of betablockers in patients with chronic systolic heart failure. The benefits include improve survival (35%) reduced need for hospitalization and improve of left ventricular function. However, betablockers may also make a patient with heart failure worse, especially when treatment begins and there is reluctance to use betablockade therapy. Complications can generally be avoided by starting with extremely low doses and increasing the dose very slowly. Despite this, further questions remain regarding the use of these agents in cardiac failure, including the role in the progression of the disease, the selection of individual betablocker, and the use in very severe disease or very old patients.

Adrenergic beta-Antagonists↗
PubMed2000

[Correlation between mantoux and tuberculin's fraction from delayed hypersensitivity skin test, in a cohort from HIV-1 positive patients, in function of immunodeficiency level, and active tuberculosis incidence].

OBJECTIVES: The aim of this work was to assess cellular immunity using the multitest CMI and relate its results with lymphocyte CD4 counts, and the risk to developed active tuberculosis if the multi-test's tuberculosis pápula was positive. METHODS: Prospective longitudinal follow-up of 342 IDU patients, 210 infected with HIV-1 and seronegative 132 patients. The cohort study was 165 IDU HIV-1 positive patients (128 men, 37 female). Ages was 18 to 45 years. Study time were 25 months (8-25). Tuberculin skin tests and multitest IMC were performed at baseline and each three months, and screening from active tuberculosis were performed all study when necessary was considered. RESULTS: Actived tuberculosis developed in 9.25 cases per one hundred persons and year from follow-up in the ranges with better immunologic status (Score from PHR > 10 mm). There are an significative correlation between tuberculosis skin test diameter and PHR tuberculin fraction papula. CONCLUSIONS: PHR performed with Multitest IMC is an useful test to evaluate cellular immune system, and HIV-1 positive patients with energy in this test or positive tuberculine fraction must be considered to isoniazid (9 months) prophylaxis.

AIDS-Related Opportunistic Infections↗
PubMed1991

[Plasmacytoma of the thyroid. A review apropos a case].

Isolated presentation of outer bone marrow plasmatic cell neoplasia are non-frequent (less than 10% of all plasmacytomas). Thyroid gland involvement is rarely described. A case where immunohistochemistry confirmed the monoclonal type of proliferative cell is presented. Clinical, pathological and diagnosis criteria, as well as response to treatment, are reviewed.

Aged↗
PubMed1990

[Alcohol withdrawal syndrome at the internal medicine department of a general hospital; epidemiology and hospital costs].

Alcohol withdrawal syndrome (AWS) is an admission problem and can also occur in hospitalized patients. We endeavoured to ascertain the exact epidemiology and hospital cost of AWS based on a review of the charts of patients admitted during 1986, 1987, 1988 (total = 78). The statistical analysis of the differences was performed by chi-square test with a significant level = or less than of 0.05. The results were: total hospital prevalence of AWS = 2.44%, hospital prevalence by season = 3.33% (spring), 2.04% (summer), 2.28% (fall), 2.19% (winter). Outpatients presentation = 79.49%, highlighting fever syndrome of unknown origin (FSUO) (16.4%) and pneumonia (11.48%); hospital presentation = 20.51% focusing acute pancreatitis (31.25%) and pneumonia (25%) as first causes of admission. The significant association between FSUO and spring and winter (84.62%); relation male: female = 5.5: 1; mean age = 42.57 years; decade distributions = 1st decade 0%, second = 1.28%, third = 11.64%, fourth = 35.90%, fifth = 24.36%, sixth = 16.67%, seventh = 8.97%, eighth = 1.28%, ninth = 0%; mean admission time = 14.12 days; total hospital cost of out-patients presentation = 15.087.370 pesetas.

Costs and Cost Analysis↗
PubMed1989

[Whipple's disease and splenomegaly with negative intestinal biopsies].

A case is presented of a patient with a picture of acute gastroenteritis and splenomegaly. Microscopic study of the spleen and a lymph node showed the characteristic findings of Whipple's disease, although no digestive alteration was found, in spite of performing several duodenal and jejunal biopsies. The etiopathogenesis of this entity is commented on and discussed.

Adult↗
PubMed1989

[Clinical forms and prognostic criteria in alcoholic hepatitis].

The biological and clinical features and prognostic factors of 65 patients affected by alcoholic hepatitis were studied. All patients had an ethanol intake higher than 80 gr/day during at least 3 years. 22 patients were female and 43 male with a mean age of 45 +/- 11.7 years. 19 had acute hepatitis (29.2%), 2 had acute hepatic insufficiency (3%), one had acute cholestasis (1.5%), 14 had chronic hepatopathy (21.5%). 29 patients had the diagnosis (44.6%) confirmed by histologic analysis. All patients had liver enlargement, 25 had jaundice and 4 had fever. The hepatic biopsies showed steatosis in 53 cases, centrilobular sclerosis in 32 cases and cirrhosis in 19.8 patients developed hepatic encephalopathy, 3 had renal insufficiency, and 4 died. The levels of albumin (P = 0.0043), total bilirubin (P = 0.0003), prothrombin (P = 0.0001) and the development of hepatic encephalopathy or/and renal insufficiency were the parameters to define the group of patients with bad evolution, the IgA also being significant. The low mortality of our studied (6.1%) can be justified by the diagnosis at non-symptomatic stage. We recommend a liver biopsy in all patients with chronic alcoholism and liver enlargement, or biologic markers suggesting alcoholic hepatopathy.

Adult↗