PubMed Health⌕ Search

Biomedical subjects

I S Bazanova

Publications and source records attributed to I S Bazanova.

At least 19 recordsLinked to original sources
PubMed1986

[Protective action of serotonin on changes in the ultrastructure of the Retzius neuron induced by acetylcholine].

A combined action of acetylcholine and serotonin is demonstrated to produce, in ultrastructure of the Retzius neuron of the leech, changes similar to those resulted from synaptic activation. Nevertheless, acetylcholine alone produces much deeper morphological shifts. A conclusion is made that serotonin not only retards impulse activity of the neuron, but it "slows down" development of rather great changes in its ultrastructure.

Acetylcholine↗
PubMed1986

[Ultrastructural changes in the mitochondria of Retzius' neuron exposed to hydrocortisone].

The ultrastructure of the Retzius cell (gigantic neurone) mitochondria of the medical leech was investigated. After seven repeated injections of hydrocortisone into the coelomic cavity, the transformation of laminar cristae of mitochondria into tubule-vesiculated structures was discovered. A question of correlation between the structure and function independently of the systematical position of the organism is discussed.

Animals↗
PubMed1982

[Functional restructuring of the ultrastructure of the giant neuron (Retzius') in the medicinal leech and the possible role of Ca++ ions in these processes].

As it has been demonstrated in the giant (Retzius') neuron of the leech (Hirudo medicinalis), at the synaptic activation for 5 sec. and 10 min., ultrastructural changes in the neuron are accompanied with an increasing number of Ca++ ions in hyaloplasm, mitochondria and cytosomes. After activation, the ultrastructural changes increase, and the number of Ca++ ions returns to the initial level. A suggestion is made on a trigger function of Ca++ ions when the neuronal ultrastructure changes under conditions of the synaptic activation.

Animals↗
PubMed1979

[Bioelectrical activity and ultrastructure of medicinal leech Retzius neurons during chronic direct and synaptic activation].

The threshold direct or synaptic 1/sec stimulation of the Retzius cells increases the firing rate of the neuron in the leach. The firing rate becomes synchronized with the stimulation applied. The membrane potential does not change. After 10 min of such stimulation changes occurring in the ultrastructure of neuron are similar to those in a neuron with no stimulation: these changes reveal a decrease in the synthetic processes whereas the bioelectrical activity remains the same which suggests a certain independence of the neuron electrophysiological parameters of its ultrastructure.

Animals↗
PubMed1978

[Characteristics of synaptic and intracellular neuron activation].

Stimulation of the leech abdominal neural chain with electric pulses of 1 imp/sec frequency results in alterations in the activity of the Retzius cells in addition to an increased protein metabolism in the postactivation period. The direct stimulation produces a decrease in the cellular protein metabolism.

Abdomen↗
PubMed1976

[Strength of synaptic stimulation and morpho-functional reorganization of the neuron].

In the Retzius cell of the leech, synaptic threshold and three-fold threshold stimulation 1/sec was followed by readjustment of the cell spike activity according to the stimulation rhythm. After cessation of the stimulation the initial bioelectrical activity restores. The membrane potential remains unaltered during the three-fold threshold stimulation. Electron-microscopically, the Retzius cells develop different ultrastructural changes. In case of the threshold stimulationthe changes indicate an intensification of the synthetic processes and, on the contrary, the three-fold threshold stimulation is followed by a decrease in the proteinmetabolism. In the first case, the amount of granular endoplasmatic reticulum increases and in the second case -- decreases. The same is true for the total amount of ribosomes. During synaptic stimulation, the Retzius cell mitochondria remain unlatered while during the three-fold threshold stimulation the mitochondria swell, their matrix clears up, and their krysts become reduced.

Animals↗