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Biomedical subjects

I S Chekman

Publications and source records attributed to I S Chekman.

At least 91 records · Page 5Linked to original sources
PubMedDate not supplied

[Pharmacological aspects of digoxin complex formation with calcium and magnesium cations].

NMR spectroscopy was used to establish the formation of digoxin and digitoxin complexes with calcium ions. Microcolorimetric titration demonstrated the formation of two types of digoxin complexes with magnesium at a ratio of 1:1 and 1:2. It was noticed in rat experiments that digoxin (2.5 mg/kg) raises the magnesium level in liver tissue, whereas in a toxic dose of 12.5 mg/kg it increases the calcium content in the heart muscle.

Animals↗
PubMedDate not supplied

[K-strophanthin-beta complexing with calcium, magnesium and dysprosium ions].

Nuclear magnetic resonance, microcalorimetry and the use of the ion-selecting electrode evidenced that k-strophanthine-beta forms complexes with the calcium, magnesium and disprosium ions. Changes in the position of the k-strophanthine-beta carbohydrate parts and aglycones signals bear witness to their participation in the complexing.

Calcium↗