PubMed Health⌕ Search

Biomedical subjects

I S Dunlop

Publications and source records attributed to I S Dunlop.

9 recordsLinked to original sources
PubMed1995

Reversible ophthalmoplegia in CPEO.

PURPOSE: To present a case of improvement of ocular motility in a patient with chronic progressive external ophthalmoplegia (CPEO) with Coenzyme Q10. METHODS: Coenzyme Q10 300 mg daily was given for three years with a three-day trial period of 200 mg daily after one year. Ocular ductions were measured by synoptophore. RESULTS: Ocular ductions improved with treatment with Coenzyme Q10. CONCLUSION: Coenzyme Q10, is effective in limiting the severity of ophthalmoplegia in this case.

Adult↗
PubMed1994

Meta-analysis of systemic anti-fibrinolytics in traumatic hyphaema.

We report a meta-analysis of randomised, controlled, clinical trials of systemic anti-fibrinolytics in traumatic hyphaema. Outcome measures were rate of secondary haemorrhage and final visual acuity. An estimate of the overall odds ratio for each outcome measure was calculated both by combining the logarithms of the odds ratios, and by the Mantel-Haenszel method. The results confirm a beneficial effect of systemic antifibrinolytics on the rate of secondary haemorrhage, but not on final visual acuity.

Antifibrinolytic Agents↗
PubMed1994

Retrobulbar botulinum toxin for treatment of oscillopsia.

Two cases are presented in which multiple episodic retrobulbar botulinum toxin injections have diminished incapacitating acquired oscillopsia and nystagmus and improved visual acuity. One transient ptosis occurred in six procedures. Improvement duration averaged approximately three months. This is a simple, safe and effective therapy where alternative treatments are typically unsatisfactory.

Adult↗
PubMed1991

Problems in the diagnosis and management of unilateral retinoblastoma.

The improved prognosis for life in retinoblastoma challenges us to readdress the severe morbidity associated with late presentation and treatment, particularly in unilateral disease. Three cases of unilateral sporadic retinoblastoma are presented to illustrate the range of therapeutic options that need to be considered in management and to show that early recognition of the tumour and local treatment have the potential to minimise morbidity and to enable binocular vision to be retained.

Antineoplastic Agents↗
PubMed1988

Visual failure in allergic aspergillus sinusitis: case report.

We present a case of rapid progressive unilateral visual loss in a 69-year-old woman who presented with facial pain, ipsilateral proptosis and restriction of eye movements, and nasal symptoms suggestive of sinusitis. A diagnosis of allergic aspergillus sinusitis was made on the basis of local histopathology and systemic features. Over a three-week period vision deteriorated to bare perception of light but showed a dramatic improvement to a level of 6/9 central vision on systemic steroid therapy. The mechanism of visual failure in the context of allergic aspergillus sinusitis and the therapeutic implications are discussed.

Aged↗