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Biomedical subjects

I S Gilgoff

Publications and source records attributed to I S Gilgoff.

6 recordsLinked to original sources

Planning an outing from hospital for ventilator-dependent children.

Returning ventilator-dependent children to the home environment has become a well-accepted occurrence. The success of a home program depends on careful pre-discharge planning in order to ensure the child's medical safety, and adequate preparation to ensure the child's and family's adjustment to an active community life after discharge. To achieve this, involvement in community activities must begin while the child is still in hospital. As part of a complete rehabilitation program, nine ventilator-dependent children were taken on an inpatient outing to Disneyland. The planning and goals of the outing are described.

Activities of Daily Living↗

Hypoventilation and apnea in children during mechanically assisted ventilation.

Uncuffed tracheostomy tubes are used for long-term mechanical ventilation in children. However, upper airway mechanics differ between sleep and wakefulness; this may affect air leak around tracheostomies. We studied 19 children with high cervical spinal cord injury on portable positive pressure ventilators, age range birth to 19 years. Ventilator settings were adjusted while awake to achieve PaCO2 less than 45 mm Hg and PO2 greater than 90 mm Hg. Clinically several children with uncuffed tracheostomies became unstable at night with seizures and sleep disruption. Nine of 11 children on volume controlled systems were found to be inadequately ventilated during sleep. Substitution with a cuffed tracheostomy allowed adequate ventilation both awake and asleep, suggesting that inadequate ventilation during sleep was due to an uncompensated leak around the uncuffed tracheostomy. To avoid cuffed tracheostomies, eight children received pressure controlled ventilation. Gas exchange was adequate throughout the day and night. We conclude that children receiving volume controlled mechanical ventilation via uncuffed tracheostomy tubes can exhibit hypoventilation due to uncompensated air leak. Pressure controlled ventilation improves adequacy of gas exchange during sleep and wakefulness.

Apnea↗

Cardiac pacemaker in high spinal cord injury.

Bradycardia followed by cardiac arrest is well documented as a complication of acute injury to the cervical spinal cord. This life-threatening bradycardia is attributed to an imbalance in the autonomic nervous system resulting from dissociation of the parasympathetic from the sympathetic responses during the stage of spinal shock. A patient with a C2 complete quadriplegia secondary to birth trauma who experienced symptomatic bradycardia, continuing for 21 months after injury despite intensive medical management, is reported. Clinical improvement followed insertion of a cardiac pacemaker. Possible etiologies for the continuation of abnormal bradycardia episodes after the resolution of spinal shock are discussed. Cardiac pacemaker implantation is advocated for patients with high cervical spinal cord injuries and continuing symptomatic bradycardia not responding to medical measures.

Birth Injuries↗

Long-term ventilatory support in spinal muscular atrophy.

Before ethical issues regarding prolonging life in patients with degenerative disease can be considered, the quality of life with medical intervention must be delineated. We have followed 15 patients with spinal muscular atrophy who have been treated with mechanical ventilation. They have received assisted ventilation for an average of 8 years 10 months (range 5 months to 23 years 10 months). Three of the patients required full-time ventilator assistance at the time of initiation of ventilation; the remaining 12 used nighttime ventilation for an average of 8 years 7 months. Nine patients continue to receive nighttime ventilation only. Two patients died after 5 years and 14 years of assisted ventilation, respectively. Of the 10 patients more than 18 years of age, three graduated from college, two are in college, three graduated from high school, and two completed eleventh grade. One patient is a mother of a healthy child. Two patients are employed, and two others have found fulfilling volunteer work. Ventilator support has not significantly interfered with these patients' plans and expectations.

Adolescent↗

Neck breathing: a form of voluntary respiration for the spine-injured ventilator-dependent quadriplegic child.

Children with respirator-dependent quadriplegia because of C-2 spinal cord injuries are now surviving the acute stages of their injury. The major cause of mortality and morbidity in the chronic stage is due to respiratory complications. Surveillance, 24 h/d, is the best way to prevent accidental disconnection of respirator equipment from the patient and its inherent catastrophic consequences. The constant risk of disconnection adds tension to the home environment and takes away from the patient any degree of independence or privacy. Because of this, an alternative method of respiration using neck accessory muscles was developed to restore a patient-controlled, voluntary system of respiration. This method, neck breathing, is described in detail in seven children varying in age from 3 years to 16 years 3 months. All seven patients had complete paralysis of the intercostal muscles and the diaphragm. An eighth patient who was unable to learn the technique is also described. Neck breathing is also compared to glossopharygeal breathing, an alternative method of respiration developed during the polio era.

Adolescent↗