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Biomedical subjects

I S Podosinnikov

Publications and source records attributed to I S Podosinnikov.

At least 19 recordsLinked to original sources
PubMed1989

[Level of the C3-component of complement in the blood serum of sick children].

The levels of the complement C3 component have been measured in children with various diseases (immunodeficiency states, food allergy, rheumatoid arthritis, severe and medium-severe forms of acute respiratory viral infections), and the complement consumption in the course of alternative activation has been examined. The findings evidence a relationship between the complement C3 component consumption and the blood serum IgA level, as well as between the C3 level and the neutrophilic phagocytic and metabolic activities.

Arthritis, Rheumatoid↗
PubMed1985

[Effect of thymectomy on carbohydrate and lipid metabolism in the rat].

12 months after thymectomy (TE), the diminution of glucose concentration, glucose metabolic products in blood and decreased activity of liver phosphoenolpyruvate carboxylase of rats were demonstrated. The disturbance of gluconeogenesis in TE rats, however, proceeded in a latent manner within 9 months. These data suggest that thymectomized animals, along with T-immunodeficiency, develop an inhibited gluconeogenesis. The thymus gland seems to influence the glucose homeostasis either directly or through some interactions with the neuroendocrine controlling system.

Adrenal Cortex↗
PubMed1985

[Structure of the thymus, iliac and mesenteric lymph nodes in the rat at different stages of pregnancy].

Development of pregnancy results in a systemic reaction of the immunogenetic organs: the structure of both the central (thymus) and peripheral lymphoid organs (lymph nodes) undergoes certain changes, beginning from its earliest stages (preimplantation period). Unidirection of the processes in the iliac (that are regional for the uterus) and mesenteric lymph nodes is stated. The reconstruction of the node occurs according to the reaction type at tissue allotransplantation, when hypertrophy of the thymus-dependent zone comes forward. During the period of the greatest manifestations of these alterations, however (the second half of pregnancy) the migration process of lymphocytes from blood into the lymph node is significantly inhibited. This is essentially clear in the iliac lymph nodes. The reconstruction of the thymus is in general similar with phenomena of accidental involution. However, accumulation of thymocytes in the medulla demonstrates blocking of their discharge into the blood stream. The disturbed processes of recirculation of result in incompleteness of the immune response at pregnancy and, perhaps, are included into the protective mechanisms of the offspring reproduction.

Animals↗