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Biomedical subjects

I S Reid

Publications and source records attributed to I S Reid.

At least 19 recordsLinked to original sources

Intussusception in Newcastle in a 25 year period.

The history of intussusception in Newcastle in a quarter of a century is presented by analysis of patient presentation and the results of management. The figures for the early years are incomplete, retrieved from one hospital in the area. For the years 1976-1988, all cases were managed by two paediatric surgeons who kept individual disease indices. One hundred and sixty-five episodes of intussusception in 153 patients were reviewed in this study. There was one death in the series, whereas there had been several in the years preceding it. There has been an improvement in the success of hydrostatic and later pneumatic reduction. These changes are attributed to the development of appropriate skills resulting from concentration of the management of this problem in the hands of paediatric surgeons and radiologists with special training and interest in paediatrics. Enema reduction has been used more aggressively in recent years and has widened criteria. In the series there were 8 patients with causal lead points, none associated with recurrence. The overall recurrence rate within the series was estimated at 8%. There seems to be a high incidence of intussusception in doctors' families.

Abdomen↗

Acute cervical lymphadenitis in children.

A retrospective study of 78 children with acute cervical lymphadenitis treated in Newcastle over the last 9 years revealed that abscesses formed in 50 children despite antibiotic treatment. Children under 2 years of age were more likely to form an abscess than older children. The commonest organism isolated was penicillin-resistant Staphylococcus. Beta-haemolytic Streptococcus was isolated less commonly and isolation of penicillin-sensitive staphylococci was rare. Penicillin and amoxycillin alone are unsuitable as first line antibiotics. Severe infections and those failing to respond rapidly to initial antibiotic treatment should be admitted to a paediatric unit for intravenous beta-lactamase-resistant antibiotics.

Abscess↗

Recurrent diaphragmatic hernia.

There are 109 cases of congenital diaphragmatic hernia reviewed. There were 58 survivors in this group. There were 13 recurrences among these 58 cases, an incidence of 22.4%. One can recognize minor and major recurrences. Minor recurrences are usually stable and nonprogressive and, in general, do not require further surgery. The technique of intercostal flap repair of recurrent diaphragmatic hernia is described. This technique has been used in five cases of recurrent diaphragmatic hernia and has proved satisfactory in every instance. It is recommended as the technique of choice in most cases of recurrent diaphragmatic hernia.

Hernia, Diaphragmatic↗

Bilateral ureteral obstruction following aortic bypass surgery.

A patient developed azotemia from bilateral ureteral obstruction due to retroperitoneal fibrosis after placement of an aortofemoral bypass graft for atherosclerosis in that region. This complication of abdominal vascular prosthesis may be more common than is presently recognized; especially since the patient may remain asymptomatic till an advanced degree to azotemia supervenes. At that time irreversible damage to the kidney may occur. Furthermore, silent damage in the kidneys may be attributed to other causes in these patients who may also have severe vascular disease or prostatic disease. When a gradually increasing azotemia is seen in a patient who had aortofemoral bypass surgery, ureteral obstruction from retroperitoneal fibrosis should be one of the main considerations in the differential diagnosis. Computed tomography, isotope renography and sonography may be helpful in making an early diagnosis and should be a part of the postoperative follow-up care in these patients.

Aged↗

The management of gastroschisis.

A review of gastroschisis treated at the Royal Alexandra Hospital for Children, Sydney, in the ten years between 1967 and 1976, was carried out. Early postoperative deaths occurred in those with poor general condition before and immediately after the operation. The presence of a gastrostomy appears to be most effective in the immediate postoperative period to assist in decreasing intraabdominal pressure. The results of three initial operative methods are discussed. The three procedures are the Gross method; prosthetic closure; and the Savage and Davey method of transverse incision and closure. The purpose of this paper is to suggest that the procedure described by Savage and Davey has been a most successful procedure in providing reliable and safe method of closure of gastroschisis, avoiding the complications and morbidity of staged closure using prosthetic material.

Abdominal Muscles↗

Congenital diaphragmatic hernia associated with homolateral upper limb malformation: a study of possible pathogenesis in four cases.

Four cases of congenital diaphragmatic hernia associated with homolateral upper limb reduction deformities are presented and are analyzed in terms of their pathogenesis. Diaphragm and upper limb are supplied by adjacent segments of cervical neural crest, and the sensitive period for upper limb formation occurs during early neural crest development. The evidence supports the possibility of cervical neural crest injury as the underlying pathogenesis.

Arm↗

Gastroschisis treated with lyophilized dura.

At the Royal Alexandra Hospital for Children, Sydney, we have found that primary closure in gastroschisis is usually successful. However, in a small number of cases such closure is found to be impossible. In such patients we have not been satisfied with silastic sheeting and have on two occasions successfully used lyophilized dura.

Abdominal Muscles↗

The effect of Marek's disease vaccination and day-old debeaking on the performance of growing pullets and laying hens.

In a 2 X 2 completely randomized factorial design, four hundred day-old Single Comb White Leghorn pullets were randomly assigned to four treatment combinations of vaccinated, non-vaccinated, debeaked and non-debeaked groups. Vaccination and debeaking were performed at day-old by administering 2,000 P.F.U. of HVT vaccine/chick and by removing approximately 2/3 of the upper beak, respectively. All the data were analyzed at 5% level of probability. Vaccination reduced feed consumption significantly only during the early growing period of the first 12 weeks, whereas debeaking caused a significant reduction in feed consumption throughout the experimental period of 80 weeks. Mortality during the 20-week growing period was not affected by either vaccination or debeaking. During the laying period (20-80 weeks of age), vaccination reduced the mortality numerically, while debeaking reduced the mortality significantly. Final body weight, hen-day egg production, egg weight, albumen height and egg shell thickness were not influenced by either vaccination, debeaking or a combination of the two. Debeaking had no effect on the incidence of blood-spotting in the eggs. Vaccination, however, significantly reduced percent blood spots in the eggs. Day-old debeaking effectively prevented the occurrence of cannibalism.

Animals↗

Long-term follow-up of patients with congenital diaphragmatic hernia.

A long-term follow-up was carried out on 30 patients who had congenital diaphragmatic hernias operated on over a 21-yr period. The review took the form of clinical examination, chest x-rays, pulmonary function tests, and lung scans. Lungs that were hypoplastic at birth remained underdeveloped as judged by pulmonary function tests and hypoperfusion on lung scan; however, children who survived birth6 and operative repair went on to live normal lives through the period studied. There was some suggestion from pulmonary function tests and lung scans that in the older group a preemphysematous state may exist but this was asymptomatic. There was no evidence of increased susceptibility to respiratory infection in the group. Ten per cent of the children were mentally retarded, evidently from hypoxia after birth.

Adolescent↗