A comprehensive evaluation was done in 162 patients-liquidators of the Chernobyl accident. Of these, 80 percent were diagnosed as having stage I and II dyscirculatory encephalopathy (DE), 20 percent were in stage III. It is shown that DE progression is caused by great strain on and breakdown of autoregulatory mechanisms of different biological systems (vascular, central nervous and vegetative, hormonal), and of central regulatory mechanisms as well. Under certain conditions there may occur their breakdown, with syncopal states, crises, and even insults developing in its wake. Treatment and rehabilitation of DE liquidators with pyracetam, vinpocetine, cerebrolysine with magne B6, and phytosorbents (spirulina, quercitrol, and vitapectine) lead to reconditioning of central and autoregulatory compensatory-and-adaptive mechanisms, long-lasting remission, provide complication prophylaxis and promote work activity.

Adaptation, Physiological↗

PubMedDate not supplied

[The characteristics of cerebrovascular disorders in persons exposed to the effect of ionizing radiation as a result of the accident at the Chernobyl Atomic Electric Power Station].

Small doses of radioactive irradiation were found to be associated with damage to all levels of the nervous system, as evidenced by cliniconeurological investigations. But regulatory functions and vascular system get it most of all. Commonly seen in the sample was vegetovascular dystonia, also revealed were a varying degree discirculatory encephalopathy, acute disturbances in cerebral circulation, dyscirculatory myelopathy. Vascular abnormalities may develop at any age but in young adulthood they tend to occur more frequently. Clinical manifestations of vegetovascular dystonia were characterized by profound mixed type vegetative crises. Even if treated, vegetovascular dystonia tends to acquire remittent-and-progredient course leading to decompensation very soon. Strokes run atypical course: hemorrhages occur more often than not; circulatory disorders come about against the background of normal arterial blood pressure or insignificant its fluctuations. Hemorrhage may run gradually progressing course, which fact makes their diagnosis very difficult even with modern techniques being involved in relevent studies. It is not infrequently that carotid angiography does not find any structural-and-morphologic changes in the main vessels. A separate nozologic form, viz. that of discirculatory encephalopacy due to radiative irradiation, is suggested, as an entity worth introducing into the medical nomenclature.

Adult↗

PubMedDate not supplied

[Clinico-structural changes in the brain in cerebrovascular insufficiency].

Overall seventy patients with chronic hypertensive encephalopathy and acute cerebral circulatory disorders were examined, their age ranging between 35 to 75 years, by ACT, MRT, USG. MRT was found out to be the most objective method for identifying structural changes in the brain in cerebrovascular disorders. The main signs of MR-tomography are vascular changes presenting as lacunar infarctions with or without perifocal area of edema, hydrocephalus, brain swelling, intracranial hypertension, poor differentiation of gray and white substances of the brain, with hygromas being readily identifiable. Lacunar infarctions, periventricular edema, dilatation of the ventricular system are regarded as equivalent of clinical signs of chronic hypertensive encephalopathy.

Acute Disease↗