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Biomedical subjects

I Senff

Publications and source records attributed to I Senff.

3 recordsLinked to original sources

[Adaptive algorithm for automatic measurement of retinal vascular diameter].

A new adaptive computer-aided method for the measurement of blood vessel diameters has been developed. Within areas of interest in the image, the algorithm detects, line-wise, the edges of the vessels, which are then used for image-wise approximation and noise filtration. A high level of adaptivity with respect to numerous measuring parameters ensures its use in a wide range of applications. Thus, it has been shown to significantly improve clinically relevant reproducibility in the area of follow-up observations. The standard deviation for vessel diameter was (2.2 +/- 0.7)% in the case of arteries and (1.8 +/- 0.5)% in the case of veins. Testing the algorithm in images of poor quality revealed its high level of reliability and sensitivity.

Algorithms↗

[Adaptive procedures for measuring arterial blood flow velocity in retinal vessels using indicator technique].

There are highly significant differences in the measuring results of arterial blood velocity between the indicator and laser-Doppler techniques (up to 800%). A new measuring procedure for the analysis of indicator dilution curves was developed based on indicator model and experimental results. The use of this new measuring procedure results in reduced mean systematic error between the indicator and laser-Doppler techniques to values around 10%. With the introduction of adaptive measuring arrays for the creation of indicator dilution curves and the application of adaptive algorithms for centering and spectral normalizing of the dilution curves, improved reproducibility can be expected.

Blood Flow Velocity↗

Filtering properties of an adaptive trend operator and the application for determining the arterial blood velocity in retinal vessels.

This study deals with methods focused on estimating blood velocity. The estimation of the linear trend function of a non-stationary signal based on the adaptive recursive estimation of the mean value function is used for the determination of the time delay of two indicator dilution curves. The filter property of this trend operator depends on the choice of a constant parameter c, the so-called adaptation factor. The functional connection between the filter property and the adaptation factor is considered in such a way that an objective calculation of arterial blood velocity in retinal vessels is possible.

Algorithms↗