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Biomedical subjects

I Sigridov

Publications and source records attributed to I Sigridov.

9 recordsLinked to original sources
PubMed2006

[Doppler velocimetry in patients with preeclampsia].

UNLABELLED: Doppler velocimetry is a fast and convenient method for monitoring of fetal well being in high risk pregnancies. Doppler velocimetry is more specific and sensitive method of fetal surveillance than cardiotocography. The study's objective is to prove Doppler's effectiveness in predicting perinatal outcome in preeclamptic pregnancies. A retrospective study is designed, including pregnant women, diagnosed with preeclampsia, admitted to Maternity hospital "Majchin dom" for ten years. Doppler study was made and results were correlated to Apgar score, umbilical artery pH and base excess of the neonate at delivery. A correlation between RI of umbilical artery, uterine arteries and Apgar score at 5th minute was demonstrated. In severe cases correlation between RI of umbilical artery and neonatal pH was found. CONCLUSION: Doppler velocimetry is an effective method of fetal surveillance in pregnancies, complicated by preeclampsia

Apgar Score↗
PubMed2006

[Effect of the blood pressure on the perinatal fetal outcome in patients with preeclampsia].

No matter the fact that the changes in the blood pressure are quite often the first clinical feature of preeclampsia, is known that they are not early, but are quite late preeclampsia symptom. Close follow-up of the blood pressure trough whole pregnancy and in preeclamptic patients plays an important role in the improvement of the perinatal outcome. Five hundred forty four singleton pregnant women were enrolled in the study. Of them 334 were with mild preeclampsia and 210 were with severe form of the disease. The analysis of correlations shows a correlation between the blood pressure at admititon and before delivery of the women with mild and severe form of preeclampsia and the perinatal fetal outcome. The fifth minute Apgar score is significantly lower in the patients with severe preeclampsia in comparison with women with mild disease. The represented data confirm the hypothesis about the influence of the maternal blood pressure on the perinatal fetal outcome.

Apgar Score↗
PubMed2006

[Cardiotocographic monitoring (non stress test) in pregnancies, complicated by preeclampsia].

Cardiotocographic monitoring (NST) is well accepted in obstetrical practice. It provides direct and valuable information about neurological and myocardial function of the fetus. In a retrospective and prospective study, including 544 preeclamptic women for period of 10 years cardiotocographic monitoring of the fetus was applied. At admission in 427 (82.80%) of the cases, CTG readings were found normal. In the rest of 89 (17.20%) preeclamptic patients the NST records were found pathological. A correlation between mean values of resistance indices (RI) of umbilical and uterine arteries (RI = 0.73; RI = 0.75 respectively) and pathological NST was demonstrated. A similar correlation is found for newborn's Apgar score at 5th minute--7.16. Although the difference is found statistically significant, it is not possible to conclude that Doppler velocimetry is more predictive than cardiotocographic records.

Apgar Score↗
PubMed2005

[Ferro-folgamma--a good alternative in the treatment of iron deficiency anemia and depleted iron stores in pregnant women].

OBJECTIVE: To study the effect of different therapeutical regimens of Ferro-Folgamma, in pregnant patients with iron deficiency anemia. MATERIALS AND METHODS: 22 pregnant patients between 20 and 35 week of gestation (mean 29 gestational week) with hemoglobin levels between 83.1-106 g/l were included. They were divided in two groups: group 1 included patients with hemoglobin levels up to 100g/l and group 2--with hemoglobin levels between 100 and 110. The dosage of the preparation in group 1 was 1 tablet Ferro-Folgamma tid for 40 days, and 1 tablet Ferro-Folgamma bid for the same period. Blood samples were taken four times during the study on day 0, 10th day, 20th day and in the week after the 40th completed day of therapy. The samples were tested for CBC, iron, transferine, feritine, folic acid. All patients were given complete information about the possible risks of iron deficiency anemia during pregnancy and parturition. DISCUSSION AND RESULTS: The mean hemoglobin level at initiation of treatment was 91.22 g/l (day 0). After initiation of treatment the the following rise in hemoglobin levels was detected 10th day - 103.8 g/l, 20th day - 112.6 g/l, after the 40th completed day - 136.0 g/l. The mean levels of the rest of hematological parameters were, day 0 - Er - 3.25 mln/microl, Fe - 7.53 micromol/l, transferine - 3.65 gr/l, feritine - 15.02 ngr/ml, folic acid - 14.08 ng/ml, vit. B12 - 219.68 pg/ml; 10th day - Er- 3.5 mln/microl, Fe - 14. 12 micromol/l; 20th day - Er - 4.10 mln/microl, Fe - 20.46 micromol/l; 40th completed day - Er- 4.69 mln/microl, Fe - 13.12 micromol/l, transferine - 3.82 gr/l, feritine - 27.42 ngr/ml, folic acid - 15.67 ng/ml, vit. B12 - 484.52 pg/ml respectively. CONCLUSIONS: Oral treatment with Ferro-Folgamma, according the described dosage regimen, demonstrates its fast and stable effect in treatment of moderate iron deficiency and recovery of depleted iron pool in pregnant patients as well. It could be administered as a prophylactic preparation for borderline anemic states.

Anemia, Iron-Deficiency↗