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Biomedical subjects

I Starr

Publications and source records attributed to I Starr.

At least 19 recordsLinked to original sources
PubMed1979

Clinical and physiological findings when the cardiac contraction is incoordinate compared with those found in matched cases with well-coordinated hearts.

A group of patients in whom the Bcg, the pulse derivative and the ventriculogram all agreed that cardiac incoordination was present has been compared with another group in which the same three tests agreed that the heartbeat was well coordinated. By pairing the cases we have demonstrated that those with cardiac incoordination showed significantly more angina pectoris, more coronary arteriosclerosis, more abnormal electrocardiograms, a slowed pulse rate and a smaller ejection fraction than did the corresponding cases. The other physiological functions measured were not significantly different in the two groups. Evidently, incoordination of the cardiac contraction is associated with other evidences of severe coronary heart disease. One can regard it as the physiological consequences of the irregular interruptions of coronary blood supply which characterize the pathological anatomy of this disease, and can expect it to appear late in its course.

Ballistocardiography↗
PubMed1976

Influenza in 1918: recollections of the epidemic in Philadelphia.

When the great influenza epidemic struck Philadelphia in 1918, the author was just starting his third year at the University of Pennsylvania School of Medicine. After a single lecture on influenza, classes for the third and fourth year students were suspended while he and his mates manned an emergency hospital, in which they worked under little or no medical supervision and in the presence of an alarming patient mortality. This essay describes what happened in the hospital, and in the city as a whole, during the pandemic. Certain features of the clinical course of most patients permit the hope that modern therapy will prevent a repetition of the horrendous mortality.

Disease Outbreaks↗
PubMed1976

A comparison of three methods of detecting ventricular incoordination in man, and the relation of their results to the amount of coronary arteriosclerosis.

The results secured by three tests for cardiac incoordination have been compared in over 100 cardiac cases. The Bcg found the abnormality more frequently than did Vgm and PDmax, the probable reasons for this are discussed. The cases in which cardiac incoordination was detected showed, on the average, more coronary arteriosclerosis than those whose hearts beat normally.

Adult↗
PubMed1975

Early and late effects of the coronary bypass operation on cardiac contractility and coordination.

In 100 cases of coronary heart disease, cardiac contractility was studied before and after coronary bypass by a flow method, the force ballistocardiogram, and by a pressure method, the carotid pulse derivative. The two methods gave very similar results in most cases, and the agreement of their averages was impressive. A marked increase in cardiac strength, reaching its maximum a month or two after operation, followed the procedure in most cases. Cardiac coordination was also improved at this time in many subjects, but complete cardiac normality was very rarely attained. This early postoperative improvement was greater in hearts judged to be weak before operation than in those judged to be normal in strength. The early cardiac improvement was seldom held in its entirety, but usually declined at a rate, which, if continued, would abolish the postoperative improvement in about three years. This rate of cardiac decline was many times faster than that found in healthy persons or in unoperated cases of mild angina as age advanced. Nevertheless, in over 1/3 of our cases followed for a year and a half or longer, their hearts were still stronger or better coordinated, or both, than they had been before operation, and there is reason to believe that the decline was leveling. At their last test, the great majority of patients still reported that subjective improvement in their angina continued. This subjective improvement was significantly related to objective improvement of cardiac contractility in our date, but there was one striking exception to this rule. Previous studies of results following internal mammary artery ligation anf the Vineberg procedure afford an important control to the present work.

Adult↗