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Biomedical subjects

I Syllm-Rapoport

Publications and source records attributed to I Syllm-Rapoport.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Behavior of creatine in red blood cells and blood plasma of adult rats following exposure to hypoxia].

Adults rats exposed to hypoxia showed a definite increase of creatine concentration in red cells and plasma. The rise in cell creatine 37 h after the beginning of hypoxia had disappeared 2 days after the end of hypoxia. It is explained by the expulsion of preformed reticulocytes from the bone marrow. The increase of plasma creatine is supposed to be due to hypoxic damage to the muscles, which release creatine into the blood stream.

Animals↗
PubMed1978

[Change in inorganic pyrophosphatase during maturation and aging of red blood cells from newborns].

The activity of inorganic pyrophosphatase (PPase) of red blood cells (rbc) from newborns is about 40% higher than that of adults. To answer the question whether the higher activity was due to the enhanced reticulocyte count of the newborn's cell population, the rbc of both newborns and adults were separated into different density subpopulations by means of isopycnic density gradient centrifugation in dextran. To judge the quality of separation in the individual age populations of rbc, the activity of glucose-6-phosphate dehydrogenase (G-6-PD) and the reticulocyte count were determined. The activity fall of PPase during maturation and aging of rbc is stronger than that of G-6-PD. The density subpopulations of rbc from newborns and adults with equal reticulocyte counts show the same PPase activities yet different G-6-PD activities. Obviously, the higher PPase activity of a cell population of newborns is due to the higher proportion of reticulocytes. The inorganic PPase is well suited as a guiding criterion to judge the maturity and age of rbc of newborns.

Adult↗
PubMed1977

Separation and characterization of red blood cells from newborns and infants during the first trimenon of life by means of a dextran density gradient. Density distribution curves of erythrocytes and reticulocytes.

Longitudinal studies on the density of erythrocytes and reticulocytes were performed by means of the isopyknic density gradient centrifugation in dextran on three mature newborns and six premature infants during the first 3 months of life. Striking changes of the density distribution curves of red blood cells took place during the first trimenon. Median density (D50) reached its maximum between the 7th and 28th day of life. D50 of reticulocytes was lower than that of the total red blood cell population and shows similar changes to the whole cell population during the first trimenon after birth. Based on the close relationship between D50 and the percentage of lightest cells, the evaluation of the percentage of the lightest cells was recommended as a simple test to study the changes in median density.

Blood Cell Count↗
PubMed1977

Creatine during bleeding anemia of rabbits.

In bleeding induced anemia of rabbits an increase of creatine in the red cells occurred, which in some cases amounted to more than 5-times the normal concentration. In all but one case plasma creatine rose as well. Reticulocytosis, increased O2-consumption of the red cells and an increased level of erythropoietin indicated active erythropoiesis and a shift towards a younger cell population. Whether the rise of red cell creatine is solely due to a higher proportion of young cells remains an open question.

Anemia↗