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Biomedical subjects

I Szabò

Publications and source records attributed to I Szabò.

4 recordsLinked to original sources

The inner mitochondrial membrane contains ion-conducting channels similar to those found in bacteria.

Patch-clamp experiments were performed on rat liver mitochondria inner membranes. Application of voltage gradients of either polarity revealed the presence of several different conductances, ranging up to 1.3 nS in symmetrical 150 mM KCl. Evidence is presented that at least those higher than 0.3 nS are substates of the highest conductance channel. Increasing matrix-side-positive (unphysiological) transmembrane voltage gradients favored the switch of the 1.3 nS channel to operation in lower conductance states. The size of these conductances, the presence of substates and the channel behavior are strongly reminiscent on one hand of the observations on the membrane of protoplasts from the gram-positive bacterium Streptococcus faecalis, [Zoratti, M. and Petronilli, V. (1988) FEBS Lett. 240, 105-109], and on the other of some properties of previously described channels of mitochondrial origin.

Animals

Developing nurse managers in Hungary.

Success in the work of nursing administrators can be realized only if they have their own sphere of competency and authority. In the Hungarian management system, however, nursing administrators are only functional leaders; they do not have authority for decisionmaking nor do they have a major leadership role. Most hand in proposals and carry out decisions made by the general director/chief physician or other leaders of the hospital. Below, an overview of the present status of Hungarian nursing administrators and a suggested new structure of management that would provide nursing administrators with a full and independent right of decision, which would greatly improve the efficiency of nursing care.

Decision Making, Organizational

Characteristic features concerning the action of prostaglandin F2 alpha (PGF2 alpha) on the microvascular territories drained by truncus jugularis.

In dogs, PGF2 alpha injected into the Arteria facialis increases the local blood flow and microvascular permeability accompanied by an important increase of lymph and salivary flow. The results of our investigations allowed us to speculate that PGF2 alpha may be an important component of the regulatory mechanism underlying salivary secretion.

Animals