Biomedical subjects

I T Borda

Publications and source records attributed to I T Borda.

11 recordsLinked to original sources

PubMed1994

Hypercoagulability in inflammatory bowel disease.

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Blood Coagulation Disorders↗

PubMed1986

The role of drug-induced illness in admissions to an intensive care unit.

All patients admitted during a 33-month period to a multidisciplinary intensive care unit were prospectively studied in order to determine the incidence and severity of drug-induced illness leading to the admission. The role of underlying diseases was assessed and the avoidability of drug-induced illness considered. Out of 1651 patients, 97 (5.88%) were admitted because of drug-induced illness; 74 of these had serious underlying diseases. 13 (13.4%) of the 97 patients died, but underlying diseases accounted for 4 of the 13 fatalities. In nearly half of the cases, the drug-induced illness appeared potentially avoidable.

Adolescent↗

PubMed1981

Food-induced heartburn: effect of osmolality.

It is a common clinical observation that certain foods cause heartburn, some by an effect on the lower esophageal sphincter and others by a direct "irritant" effect on the esophagus. This study investigated the effect of solution osmolality in the production of esophageal pain. Subjects were divided into an "acid-positive" and "'acid-negative" group using a conventional Bernstein test. Six (54%) and 9 (82%) of 11 acid-positive subjects developed pain with hypertonic saline and sucrose (630 mOsm/kg water). One of 15 acid-negative subjects developed pain (p less than 0.01). This study suggests that foods with high osmolality are the cause of pain in the acid-sensitive esophagus.

Esophagus↗

PubMed1976

Drug surveillance data in a Canadian hospital.

Comparison of results of a Canadian hospital-based drug surveillance program with data from centres in the United States and Israel showed no important difference in the rate of drug exposures or adverse reactions. Drugs for symptomatic relief were frequently used in the Canadian centre. Women received more drugs and had more adverse reactions than men. Life-threatening and potentially fatal reactions were caused by commonly used drugs; autopsy findings may detect previously unsuspected relations between drug events and mechanisms of death. Voluntary reporting and intensive monitoring are both important in the field of adverse drug reactions.

Canada↗

PubMed1975

Coagulation studies in ulcerative colitis and Crohn's disease.

Thromboembolic disease is a known complication of ulcerative colitis, but is rarely reported in Crohn's disease. In this study, we have tried to determine if there are indeed coagulation abnormalities associated with these two diseases. Four groups of patients were studies: (1) patients with ulcerative colitis; (2) patients with Crohn's disease; (3) patients with other diseases; (4) healthy control subjects. In both disease groups, platelet counts, factor V, factor VIII, and fibrinogen levels were found to be elevated, while antithrombin III levels were decreased.

Adolescent↗

PubMed1974