[Clinical x-ray and radionuclide diagnosis of tumors and tumor-like diseases of the ribs].
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Biomedical subjects
Publications and source records attributed to I T Knysh.
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The study of 819 cases of tumors and tumor-like lesions of long tubular and flat bones and 139 cases of chronic fistulous osteomyelitis formed the basis for identification of malignant transformation-causing factors and development of measures for preventing secondary bony sarcomas.
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The authors describe results of the individual endoprosthesis of joints and defects of extremity bones in 84 patients treated for skeleton tumors. In 80 of them positive results were obtained. In three patients the results were unfavourable. There were no complications due to the construction of individual endoprostheses.
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TI-2NOMO skin melanoma patients revealed pronounced functional disturbances of the pineal gland and pituitary-adrenal system. The decline in functional activity of the former was manifested by a decrease in urine excretion of melatonin. Enhanced levels of blood ACTH, alpha-MSH and cortisole pointed to the activation of pituitary-adrenal system which was particularly high in males. The degree of endocrine disorders was found to be in correlation with tumor stage. As far as pathogenesis of the lesion is concerned, preparations which bring function of endocrine glands to normal should be adjuvant to available treatment modalities for melanoma.
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Organ-preserving operations were performed on 82 patients with malignant tumors of bones. In 58 patients osseous alloplasty was used for substitution of the defects, in 24 patients the defect was substituted by endoprosthesis after resection of the joint ends. Indications for different preserving operations are given.
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