PubMed Health⌕ Search

Biomedical subjects

I TAMM

Publications and source records attributed to I TAMM.

At least 19 recordsLinked to original sources
PubMed1965

COXSACKIE A9 VIRUS: MUTATION FROM DRUG DEPENDENCE TO DRUG INDEPENDENCE.

During the multiplication of Coxsackie A9 virus dependent on 2 - (alpha - hydroxybenzyl) - benzimidazole there arise some drug-independent virus particles, which are either drug-resistant or drug-sensitive. We studied the properties of such revertant particles under conditions which did not favor the selection of resistant over sensitive virus particles. These particles exhibited a wide range of responses to 2-(alpha-hydroxybenzyl)-benzimidazole, from high sensitivity to high resistance. Subclones showed the same degree of sensitivity or resistance as the respective parent clones.

Benzimidazoles↗
PubMed1963

Base composition of the RNA of a reovirus variant.

A variant of reovirus 3, Dearing strain, isolated after repeated pdssage of the original Dearing virus in L cells, is similar to the parent virus in many ways. It is, however, less sensitive to specific antibodies and metabolic inhibitors, and is released from L cells to a lesser extent than the original virus. Calculated as moles per 100 moles of total base in RNA, the percentage of guanine is 20.2, adenine, 29.8, cytosine, 21.0, and uracil 29.1. These values closely approximate those reported previously for the parent virus.

Adenine↗