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Biomedical subjects

I Tarján

Publications and source records attributed to I Tarján.

At least 19 recordsLinked to original sources
PubMed2006

Oral health in 8-9 year-old children in Saxony-Anhalt (Germany) and in two Hungarian cities (Budapest and Debrecen).

OBJECTIVE: This paper reports the results of standardised oral examination (dmft/DMFT, CPI) of 1,090 8-9 year-old children from Saxony-Anhalt (Germany) and 906 8-9 year-old children from Budapest and Debrecen (Hungary) to assess the oral health condition after the political changes and the transformation of the dental care systems in Eastern Germany and in Hungary respectively. METHOD: Children were randomly selected from urban and suburban areas in one of the new Federal States of Germany. Hungarian children were selected from Budapest and Debrecen. The clinical examinations were based on WHO criteria. RESULTS: The mean dmft of the German children was 3.5 (95% CI: 3.33-3.68); the corresponding mean in the Hungarian sample was 2.3 (95% CI: 2.19-2.55). In both samples the decayed (d) component was the highest within the dmft. The mean DMFT in the German sample was 0.7 (DT = 0.4, FT = 0.3, MT = 0); in Hungary the corresponding means were 0.4 (DT = 0.3, FT = 0.1, MT = 0). Initial inflammation was the most common gingivial condition found. CONCLUSION: In general the oral health status of both groups was poor. The major problem was the high percentage of children with caries that needed treatment.

Child↗
PubMed2002

The influx of serum albumin to enamel matrix in rat incisors after trauma.

The most frequent results of trauma to tooth germs are enamel hypoplasia and enamel hypocalcification. These differing results may be due to the stage of amelogenesis at which trauma occurs. The cellular and biomolecullar events involved in the genesis of these defects are poorly understood. We hypothesized that one factor involved is the possibility that relatively high levels of serum albumin enter the enamel matrix through the damaged enamel organ, and impair mineralization of the matrix. The present study was undertaken to immunohistochemically and autoradiographically localize serum albumin in the enamel organs of rat incisors after trauma was inflicted to the mandibular incisor region of 4-day-old rats. Hemorrhage was seen surrounding the enamel organ and between the detached secretory-stage ameloblasts. One day after trauma, the most intense immunohistochemical (IHC) staining for albumin was localized in the outer layer of the enamel matrix adjacent to the detached secretory-stage ameloblasts. Albumin was also detected autoradiographically in the secretory-stage ameloblasts layer and enamel matrix. These findings indicate that serum albumin can leak between the detached ameloblasts and penetrate the enamel matrix after trauma. Leaked albumin was still present in the matrix during the maturation stage. Leaked albumin in the developing enamel could inhibit crystal growth and result in hypocalcification.

Ameloblasts↗
PubMed2001

Dental trauma in children presenting for treatment at the Department of Dentistry for Children and Orthodontics, Budapest, 1985-1999.

Data on children with dental trauma who presented for treatment at the Department of Dentistry for Children and Orthodontics in Budapest over a period of 15 years were analysed. The WHO guidelines were used to classify the traumatic injuries. A total of 590 children were involved, 810 teeth being affected. Children aged 7-14 years made up 88% of the cohort. The male:female ratio was 58:42. The permanent:primary ratio for the affected teeth was 90:10. The teeth most commonly affected were the maxillary central incisors. In 70% of the cases, only one tooth was traumatised. The incidence of dental trauma peaked at 10 years of age. The most common injury type observed was enamel-dentin crown fracture. The decreasing sequence of frequency of etiological factors was playing, sports, falls, cycling, road accidents and fighting. Of the accidents, 65% occurred at school or at home. Seventy seven per cent of the patients presented for medical care in the first 3 days after the accident.

Accidental Falls↗
PubMed2001

[Frequency of supernumerary teeth and possibilities of treatment].

According to dental literature, the frequency of supernumerary teeth is 1-3%. The authors analyzed the orthopantomograms of 1875 children and adolescents aged between 6 and 18 years to determine the frequency of supernumerary teeth at the Department of Dentistry for Children and Orthodontics. The frequency was found to be 1.92%. The sequence of frequency of supernumerary teeth was: mesiodens, lateral incisor, central incisor. 77.8% of the supernumerary teeth occurred in the maxilla, 97.2% in the frontal region. Besides the data found, two successful cases of surgical and orthodontic treatment are also presented.

Adolescent↗
PubMed2001

[Prevalence of congenital hypodontia in the permanent dentition and its treatment].

Congenital aplasia (agenesis) is an important development dental anomaly. There is a big discrepancy between the data on the prevalence of aplasia in dental literature. The authors analyzed orthopantomograms of 1875 children and adolescents at the Department of Dentistry for Children and Orthodontics of Semmelweis University. The prevalence of congenital aplasia was found 15.68% (294 subjects). There was no difference between the sexes. The most frequently missing teeth were the upper lateral incisors, the lower second premolars, the upper second premolars and the lower central incisors. The highest number of aplasia was detected in the second premolars (330 teeth). The frequency of aplasia of the molars was 0.74%. Oligodontia was found in 1.12%. The authors present two patients with aplasia and the successful treatment of the cases.

Adolescent↗
PubMed2001

[Effect of experimentally induced trauma to the incisors in rats].

The purpose of this study was to produce developmental lesions of enamel in rats by a quick and simple method and to examine the enamel hypoplasia caused by trauma. 4-day-old and 3-week-old Wistar rats were used. Trauma was produced by needle pricking and hitting on the mandibula. After one week incisors were removed together with jaws and prepared for microradiography, X-ray diffraction, light microscope and transmission electron microscope examination. Microradiographic findings in the needle pricking group revealed hypocalcified and hypoplastic enamel. The incidence was 73.7%. In the hitting group of 4-day-old rats the incidence was lower, 70.0%. Microradiographic findings in this group were diffuse hypoplasia in the surface enamel. Hitting of 3-week-old rats produced no enamel hypoplasia. Crystallinity of hypoplastic enamel was reduced in both a-axis and c-axis direction. Histological findings in 4-day-old rats revealed disarranged and detached ameloblasts at location trauma. These results indicate that a needle pricking method involving secretory stage ameloblasts of 4-day-old rat incisors can induce a considerable amount of enamel hypoplasia.

Ameloblasts↗
PubMed2001

[Dental treatment of handicapped children under general anesthesia].

Complex dental treatment of a 15-year-old mentally retarded boy was presented by the authors. Oral surgical, restorative dental, and prosthetic intervention (upper and lower bridge) was done partly with intravenous narcotic agent (Propofol) and partly under intubation narcosis.

Adolescent↗
PubMed1999

Endodontic treatment of immature tooth with dens invaginatus: a case report.

The endodontic treatment of a dens invaginatus in an immature permanent upper lateral incisor of a 9-year-old boy is presented. Root canal treatment was performed using calcium hydroxide paste as a temporary root canal filling in order to achieve apexification. This was replaced after closure of the apex with a final root canal filling using gutta-percha and AH 26 as the sealer. The follow-up radiographic control demonstrated the effectiveness of nonsurgical treatment in a case of incomplete root formation in a tooth with dens invaginatus.

Calcium Hydroxide↗
PubMed1990

General anaesthesia of out-patients in pedodontics.

Complete dental treatment of 180 children has been undertaken under general anaesthesia. Indications for this were mental retardation and dental fear. Because of the simple technique and advantageous pharmacological properties, ketamine, and later its Hungarian analogue, Calypsol, were used.

Adolescent↗
PubMed1989

[Ambulatory anesthesia in pediatric dentistry].

Complex dental care has been performed on 180 mentally retarded children difficult to manage in general narcosis. Ketalar (Parke-Davis) employable also im. and iv. and its Hungarian counterpart the Calypsol (Köbányai Gyógyszerárugyár), respectively, was employed for narcotics.

Ambulatory Care↗
PubMed1986

Phage T7-inactivation test. A possibility of quantitative mutagenicity screening.

A new method is described for the quantitative characterization of the genotoxic effect of chemicals. The method is based on the determination of the inactivation of bacteriophage T7 and on the application of a simple mathematical model valid for the processes during, or at least in the initial stage of the interaction of chemicals and phages. A value characteristic for the chemical is defined and it is determined from the inactivation kinetics. Typical inactivation kinetic curves and some problems of the application of the model as well as the mutagenicity index values determined for about 30 substances are presented. The substances examined have mutagenicity index values covering a range of six orders of magnitude. The obtained values are compared with the results of different mutagenicity/carcinogenicity tests and discussed on the basis of data in the literature. The presented method is proposed to be applied for quantitative mutagenicity screening of chemicals.

Kinetics↗