PubMed Health⌕ Search

Biomedical subjects

I Transbol

Publications and source records attributed to I Transbol.

14 recordsLinked to original sources
PubMed1977

Serum and erythrocyte magnesium in normal elderly danish people. Relationship to blood pressure and serum lipids.

Serum lipids, blood pressure, and magnesium levels in serum and erythrocytes have been measured in 73 men and women, aged 60. The purpose was to evaluate the relationship between the serum and erythrocyte magnesium and indicators of ischaemic heart disease. The results showed significant inverse correlations between serum magnesium levels and PB, and positive significant correlation between erythrocyte magnesium and serum cholesterol.

Age Factors↗
PubMed1976

Control of calcium absorption: effect of sodium chloride loading and depletion.

In six out of eight patients with normal parathyroid function and in two subjects with hypoparathyroidism, sodium chloride loading was shown to increase calcium absorption as measured by the 47Ca absorption test. Although no significant change was seen in the renal and fecal excretion of calcium, a slight decrease in total serum calcium did occur with increased sodium intake. The change in calcium absorption was not accompanied by a detectable change in calcium balance. Therefore, a compensatory change in gastrointestinal calcium secretion must have occurred. Sodium intake has an effect on calcium in the gastrointestinal tract, which is independent of parathyroid hormone. Sodium intake should be considered when results of studies of calcium metabolism are compared.

Calcium↗
PubMed1976

Observations on the different calcium metabolic patterns in sarcoidosis. A metabolic and kinetic study.

Combined calcium balance and 47Ca turnover studies in sarcoidosis (4 patients) and vitamin D intoxication (1 patient) disclosed three different patterns of calcium metabolism. On patient with sarcoidosis had a normal metabolism of calcium, and two patients presented the usual pattern of intestinal hyperabsorption, hypercalcemia, and hypercalciuria. The fourth patient with sarcoidosis and the patient with vitamin D intoxication, both studied during spontaneous remissions, presented the third pattern. The main features here were hypercalcemia despite normal intestinal absorption of calcium, enlarged exchangeable calcium pool, accelerated accretion and resorption rates, hypercalciuria, and a distinctly negative calcium balance. This pattern of remission seems to represent a mobilization of extraosseous or metastatic calcifications, rather than a resorption of bone calcium.

Adult↗
PubMed1976

Urinary cyclic AMP. Relation to albumin-corrected serum calcium in healthy persons and patients with primary hyperparathyroidism.

In 21 healthy volunteers, mean excretion of cyclic adenosine 3',5' monophosphate (cAMP) in urine was 4.2 +/- 1.0 (S.D.) mumol cAMP/24 hours, 3.0 +/- 1.2 mumol/g creatinine and 3.8 +/- 1.2 mumol/24 hours/100 ml/min renal clearance of creatinine (CCr). An inverse correlation exists between the excretion of cAMP and serum calcium corrected for variations in serum albumin, most clearly demonstrated when cAMP is expressed as mumol/24 hours/100 ml/min of CCr (r=-0.630, p less than 0.01). In 21 patients with operatively verified hyperparathyroidism, the mean urinary excretion of cAMP/24 hours was 5.0 +/- 1.9 mumol uncorrected, 4.8 +/- 1.8 mumol/g creatinine and 6.6 +/- 2.1 mumol/100 ml/min of CCr. The latter two of these parameters differ significantly from the normal group (p less than 0.001), but conceal the fact that many patients with hyperparathyroidism excrete normal amounts of cAMP in the urine, independent of the mode of calculation. However, when cAMP is correlated to albumin-corrected serum calcium, this overlap between hyperparathyroidism and normality disappears completely. The results support the concept that cAMP excretion is influenced to a considerable degree by the biological activity of circulating parathyroid hormone. They also indicate that the simultaneous measurement of cAMP in urine and albumin-corrected calcium in serum is a useful aid in distinguishing hyperparathyroidism from the state of normality.

Adolescent↗
PubMed1975

Osteopenia and dysregulation of divalent cations in lithium-treated patients.

The bone mineral content (BMC) in both forearms (highly correlated to total body calcium) was measured by photon absorptiometry in a representative sample of manic depressive patients receiving lithium treatment. The mean BMC values were 93% of normal, and the mean increases in serum levels of calcium and magnesium were 2mg/l. The incidences of osteopenia, hypercalcaemia and hypermagnesaemia were 16, 12, and 30%, respectively. These results indicate that lithium-treated manic depressive patients have a disturbance in the mineral metabolism, be it due to the disease or the treatment given.

Adult↗