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Biomedical subjects

I V Chichenina

Publications and source records attributed to I V Chichenina.

8 recordsLinked to original sources
PubMed1990

[The genetic markers of psoriasis].

HLA-A, B, and C antigens were studied in 220 psoriasis patients by Terasaki and McLelland's lymphocytotoxic method. The value of relative risk for HLA-B13 and HLA-B17 antigens was estimated: 5.3 and 7.7, respectively. The detected regularities in histocompatibility antigens distribution suggest that typing of psoriasis patients may help predict, with some certainty, the course of the disease, its pattern, and clinical picture.

Adolescent↗
PubMed1989

[Clinical characteristics of psoriasis in middle-aged and elderly subjects].

Clinical features of psoriasis have been examined in 113 elderly and senile patients. The incidence rate of complicated forms of the dermatoses, associated with manifest subjective sensations, is higher in this patient population than generally in psoriasis. Clinical and laboratory studies have revealed a number of concomitant diseases contributing to the severe course of psoriasis. Combined therapy of elderly and senile patients suffering from psoriasis included drugs normalizing metabolic processes, improving the functions of the liver, cardiovascular and nervous systems.

Aged↗
PubMed1989

[The function of the monooxygenase system of the liver in patients with psoriasis].

Liver monoxygenase system function has been examined in psoriasis patients and possible modifications of current methods of therapy analyzed with due consideration for the detected disorders. A total of 139 patients with various clinical forms of psoriasis have been examined. The function of the liver monoxygenase system has been examined with the use of antipyrine test. The studies have revealed that this system's disorders are most marked in the patients with psoriatic eruptions involving a significant area, in whom the disease runs a protracted severe course. Twenty patients with normal and impaired functions of the monoxygenase system have been administered combined treatment including zixorin (600 mg orally once a week). The results evidence that zixorin improves the therapy efficacy, particularly in the patients with depressed activity of the liver microsomal enzymes. PUVA therapy has been administered to some patients. Zixorin has alleviated the side effects of phototherapy.

Adolescent↗