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I V Filatov

Publications and source records attributed to I V Filatov.

10 recordsLinked to original sources
PubMedDate not supplied

[Computation of the structure of collagen molecule fragments].

Step-by-step computations of octapeptide structures was performed for human collagens I and III. It was shown that computational results (coordinates of atoms) practically coincide with X-ray data for the collagen fragment.

Collagen Type I↗
PubMedDate not supplied

[Study of beta-turns in globular proteins].

The formation of beta-turns in globular proteins has been studied by the method of molecular mechanics. Statistical method of discriminant analysis was applied to calculate energy components and sequences of oligopeptide segments, and after this prediction of I type beta-turns has been drawn. The accuracy of true positive prediction is 65%. Components of conformational energy considerably affecting beta-turn formation were delineated. There are torsional energy, energy of hydrogen bonds, and van der Waals energy.

Hydrogen Bonding↗
PubMedDate not supplied

[The DIC syndrome as a complication of the surgical treatment of urolithiasis in urology patients].

The authors discuss the causes of the DIC syndrome in urological patients operated on for urolithiasis. They enumerate the factors predisposing to the DIC syndrome and causing it. The predisposing factors are chronic renal insufficiency and metabolic disorders caused by azotemia, infectious inflammatory complications of urolithiasis, and intoxication. The causes of the disease are massive blood loss involving disorders of the hemodynamics and blood rheology, bacterial shock, and other stress conditions. A protocol for treating this complication and validation of pathogenetic therapy is offered.

Clinical Protocols↗