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I V Lymarenko

Publications and source records attributed to I V Lymarenko.

2 recordsLinked to original sources
PubMed2005

[Adenine triphosphate-sensitive potassium channels: classification, structure and functions].

The review is dedicated to classification, structure and function of ATP-sensitive potassium channels. A general classification of K+ channels into families is based upon the primary amino acid sequence of the pore-forming subunits. The earliest classification of potassium channels was made according to the main mechanism of activation or opening of the channels. Activation of the voltage-sensitive channels is regulated by changes in the membrane potential, and of the ligand-sensitive channels by a number of ligands (calcium ions, ATP, neurotransmitters and G-protein).

Adenosine Triphosphate↗
PubMed2005

[The comparative study of the effect of new fluorine-containing guanidine-derivate compounds and pinacidil on contractile function of the urinary bladder in vitro].

The effects of the new fluorine-containing guanidine-derivate compounds on bladder contractile functionwere examined on isolated bladder strips in vitro. Female rats (250-350 g) were used. The bladder was removed and placed in the room temperaturePSS of the following composition (mM): NaCl (118.4), KCl (4.7),CaCl2 (2.5), MgSO4 (1.2), KH2PO4 (1.2), NaHCO3 (24.9), and D-glucose (11.1) gassed with O2-CO2. 95%-5%. The base of the bladder was then cut into strips 4-to 5-mm wide and 10-mm long. Then strips were pretensioned (0.25-0.5 g) and after 30 min of equilibration were contracted with an additional 60 mM KCl and again were allowed to equilibrate. Compounds were administered directly into the tissue bath. All compounds produced a concentration-dependent relaxation of isolated rat bladder strips.

Adenosine Triphosphate↗