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Biomedical subjects

I V Maev

Publications and source records attributed to I V Maev.

At least 19 recordsLinked to original sources
PubMed1992

[Hemodynamic changes in bundle-branch block].

The paper gives the data on hemodynamic features in patients with bundle-branch block. Based on the data available in the literature, the authors outline hemodynamic abnormalities occurring in various bundle-branch blocks, mechanisms of their development, influences of hemodynamic changes occurring in the blocks on the general condition of patients.

Blood Pressure↗
PubMed1992

[Doppler echocardiographic assessment of left atrial and left ventricular function during right bundle branch block].

Electrocardiographic, echocardiographic and Doppler echocardiographic studies were performed in 44 patients with coronary heart disease and complete right bundle branch block. The patients were found to have an impaired phase pattern of left ventricular systole and diastole as more prolonged length of its isometric relaxation and contraction, lower economic feasibility and efficiency of its contraction, moderate dilation and hypertrophy. Hemodynamic abnormalities in the left heart in these patients are closely correlate with the changes in the phase pattern of right ventricular systole and they turn out to be so greater as the degree of its hypertrophy is. In complete right bundle branch block, left ventricular pump dysfunction leads to decreased cardiac output and cardiac index, increased total peripheral vascular resistance, thus predisposing to impaired greater circulation.

Adult↗
PubMed1992

[The action of the new beta-adrenoblocker Lopressor on the hemodynamics of hypertension patients].

The authors carried out a complex clinico-instrumental investigation of the effect of a new cardioselective beta-blocking agent leprozor in 116 patients with hypertensive disease (stage II). A quantitative evaluation of the hemodynamics of the left compartments of the heart with two-dimensional echocardiography was carried out. Evaluation of the efficacy of using leprozor in this category of patients was based on an analysis of the state of their hemodynamics against the background of systematic intake of the drug for 7 months. Selection of the dosage was individual under the control of circulation parameters. It is concluded that leprozor proved effective in normalization of the hemodynamics in patients with hypertensive disease.

Adult↗
PubMed1992

[The function of the left heart in blockade of the left bundle of His].

A complex Doppler echocardiographic study was performed in 134 patients with complete block of the left bundle branch, its anterior branch or with concurrence of these two types of intraventricular conduction disturbance. The authors identified 5 types of paradoxical ventricular septal motion, which were related to the specific features of intraventricular asynchronism and ventricular electric systole. Type I shows the greatest decrease in left ventricular contractility, left atrial overload and phasic destruction of left ventricular systole, which reflects the processes of depolarization and repolarization propagation in the myocardium. Type IV is characterized by the lowest number of hemodynamic abnormalities. Cardiac hemodynamics is also related to the type of intraventricular block, being the least changed in isolated anterior left bundle-branch and the most changed in concurrent anterior branch and entire left bundle-branch block.

Adult↗
PubMed1992

[The Doppler sonographic measurement of the blood flow in the portal vein system in portal hypertension].

Diagnostic potentialities of Doppler sonography in assessment of portal hemodynamics in patients with chronic active hepatitis and hepatic cirrhosis were compared to those of noninvasive (rheohepatography) and invasive (angiography) techniques. Dopplerograms of the portal vein and its branches are described in specific details. Meals and treatment with beta-adrenoblockers reducing portal hypertension are evaluated in relation to their influence on the portal hepatic circulation.

Adolescent↗
PubMed1991

[New trends in the treatment of hemodynamic disorders in liver cirrhosis].

The paper reviews literature data available and first-hand experience in relation to hemodynamics of portal blood flow, lesser and greater circulation in patients with chronic diffuse hepatic diseases. Relevance of circulatory changes to hepatic lesions is also considered. With regard to specific features of hemodynamic disturbances in hepatic lesions it is suggested to use cardiovascular drugs. A pharmacodynamic effect is compared for beta-adrenoblockers, calcium antagonists and nitrates administered to patients with affected hepatobiliary system.

Adrenergic beta-Antagonists↗
PubMed1991

[Study of the right heart and external respiratory functions in patients with liver cirrhosis by Doppler echocardiography].

The paper presents clinical and instrumental evidence on 47 patients with hepatic cirrhosis. The revealed ventilatory disorders and worse bronchial permeability closely correlated with the degree of pulmonary hypertension which in its turn depended on portal hypertension degree. Pulmonary hypertension decreased with a decline in the activity of the pathological process in the liver due to treatment. External respiration insufficiency observed in hepatic cirrhosis contributes to the onset of arterial hypoxemia and hypoxic impairment of the liver activating in it a pathological process. It is recommended that such patients should receive a combined treatment incorporating oxygen therapy, calcium antagonists, antioxidants.

Adult↗
PubMed1991

[Central and pulmonary hemodynamics in patients with various forms of ischemic heart disease].

Two-dimensional and Doppler echocardiographies were used to examine right cardiac and pulmonary hemodynamics in patients with various types of coronary heart disease (CHD). All the patients were divided into 3 morphofunctional groups of CHD according to the left ventricular volume/mass index. They all were found to exhibit decreased left cardiac contractility and pump function, parallel with moderately elevated pulmonary pressure and right cardiac compensatory hyperfunction, which was largely evident in hypertrophic morphofunctional CHD. The degree of pulmonary hypertension was related to the severity of left ventricular pump dysfunction, but to its disturbed contractility in the dilated type.

Adolescent↗
PubMed1991

[Pulmonary hemodynamics in patients with hypertension during acute drug tests using obsidan and corinfar].

Two-dimensional and Doppler echocardiographies were used to examine 102 hypertensive patients who were found to have pulmonary hypertension, whose manifestation was determined by the degree of arterial hypertension, cardiac contractile insufficiency and diminished left heart pump function. The degree of pulmonary hypertension was related to the hemodynamic type and maximal with hypokinetic circulation when the pump function of the heart was minimal. Obsidan caused a decrease in pulmonary and systemic arterial hypertension, producing higher effects with hypokinetic hemodynamics. Corinfar was demonstrated to attenuate pulmonary hypertension to a greater extent. Its action on systemic arterial hypertension was highest in patients with hyperkinetic circulation. Heterodirectional hemodynamic effects of these drugs make it expedient to study their combined action on the hemodynamic of hypertensive patients.

Adult↗
PubMed1991

[Drug therapy of pulmonary and portal hypertension in liver cirrhosis].

Detailed examination of hemodynamics in patients with portal and pulmonary hypertension was performed upon acute drug tests and course administration of nitrosorbide++, corinfar and propranolol. Ultrasound and rheography investigations were employed to elucidate the relations between portal and pulmonary hypertension in cirrhosis patients. Criteria of early diagnosis are discussed. Nitrosorbide++ produced positive effect on hepatic blood flow, corinfar improved pulmonary hemodynamics in lack of its influence on hepatic blood flow, while propranolol resulted in the drop of both portal and pulmonary hypertension, normalization of general hemodynamics.

Adult↗
PubMed1991

[Hemodynamics of the lesser circulation in patients with ischemic heart disease during acute obsidan test].

During acute obsidan testing, the hemodynamics was evaluated in the pulmonary circuit and right heart cavities of 60 patients with Functional Classes III-IV exertional angina pectoris, by using two-dimensional and Doppler echocardiographies of the pulmonary artery. According to the left ventricular myocardial volume/mass ratio, the patients were divided into 3 morphofunctional types of coronary heart disease (CHD). All the patients were found to have diminished contractility and pump function in the left heart along with moderately elevated blood pressure in the left heart and compensatory hyperfunction in the right heart, which are largely evident in the hypertrophic morphofunctional type of CHD. The degree of pulmonary hypertension was related to the severity of left ventricular dysfunction, whereas in the dilated type it was associated with its contractile disorders. In patients with the dilated and mixed types of CHD, obsidan caused a marked decrease in pulmonary hypertension, while in those with hypertrophic CHD it promoted its slight increase.

Adolescent↗
PubMed1991

[Liver function in biliary tract dyskinesia].

The authors analyze data obtained in a complex clinico-instrumental study of the functional activity of the liver, portal and hepatic blood flow in 77 patients with different forms of dyskinesias of the biliary tract. Obtained data evidence in these patients development (against the background of cholestasis) functional insufficiency of the liver and involvement of its parenchyma associated with a moderate pressure increase in the portal vein, reduction of the hepatic blood flow intensity, increase of its lability that may be a proof of development (in patients with functional bile secretion disorders) of chronic diffuse inflammatory process in the liver with subsequent appearance of clinically clear portal hypertension.

Adolescent↗