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Biomedical subjects

I V Mudryĭ

Publications and source records attributed to I V Mudryĭ.

At least 19 recordsLinked to original sources

[The toxic and hygienic characteristics of the new synthetic organic flocculants AES-5, AES-7 and AES-10].

A toxicological and hygienic characterization is submitted of novel synthetic organic flocculant AEC-5, AEC-7, AEC-10 which are low-toxicity substances and are classified under the fourth class of hazards. They have no skin-resorptive, locally irritative action and are endowed with a weak cumulative activity of functional character. The AEC-5 flocculant exerts a moderately manifest sensitizing effect in the dermal route of entry.

Acrylic Resins↗

[The toxicological-hygienic characteristics of surface-active substances used in the technological processes of the oil-producing industry].

The authors suggest two stages of ecological and hygienic evaluation of surface active substances widely used in oil extraction. Stage 1. Toxicological-hygienic evaluation of these substances. Stage 2. Ecological-hygienic aspects of surface active substances (migration into soil, phytotoxicity, effect on the water quality and oth.). It was established at stage 1 that proxanol, proxamin, diproxamin are compounds of minor hazard (class 4 hazard). These substances belong to local skin-irritating substances. Proxanol produces skin-resorptive effects which is confirmed by clinical signs of intoxication, reduction of weight of the experimental animals.

Amines↗

[Hygienic significance of surface-active substances in the conditions of soil contamination with chemical substances].

Urgent problems of the interaction of surface-active substances (SAS) with other ingredients under the conditions of chemical soil pollution are discussed, in particular, under the conditions of irrigation of agricultural fields with treated municipal sewage containing detergents. Before the beginning of the irrigation season the content of anion SAS in the arable layer of the soil is 2.02-2.66 mg/kg. In the middle of the vegetation period the quantity of detergents is increased 3-4 times fold. The authors suppose, that SAS may influence translocation of heavy metals from soil into plants. However, this question should be studied more carefully in the conditions of field experience with various SAS concentrations in soil.

Agriculture↗

[The characteristics of the allergenic and skin-irritating properties of surface-active substances].

Results are discussed of research studies on hygienic evaluation of the most spread surface-active substances in the USSR Hungary. Anionic substances were shown to possess the most pronounced skin-irritating effect while amphoteric substances were shown to possess the most pronounced skin-irritating effect while amphoteric substances produced the least effect. For efficient joint studies the Soviet and Hungarian methods should be unified.

Allergens↗

[The effect of surface active substances on the barrier properties of the skin].

It was established in experiments conducted on white rats that application to the skin of sulphonol and cintamide--5 for a period of three months result in morphological disorders of the ultrastructural organization of the epidermis, especially of the structure of intercellular contacts. A mixture of these substances produces a more severe noxious effect on the structures. These substances produced also a local effect on the skin microcirculation. The authors propose a scheme for explanation of the mechanism of structural-functional changes of the skin in local applications of surface-active substances.

Animals↗