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Biomedical subjects

I V Musatova

Publications and source records attributed to I V Musatova.

At least 19 recordsLinked to original sources

[Characteristics of collateral circulation in the ophthalmic artery before and after cerebral revascularization in patients with multiple occlusive diseases of the major arteries of the head].

The status of the collateral blood flow was examined before and after establishment of ++extra-intracranial microarterial anastomosis (EICMA) in 70 patients with occlusion of the internal carotid artery. Of these, 93% of the patients also had lesions of the other main arteries of the head. It has been established that in concomitant lesions of the main arteries of the brain, the role of the ophthalmic artery (OA) rises as to the compensation for the blood flow in the damaged hemisphere. Involvement of the ophthalmic anastomosis into blood supply of the damaged hemisphere was found to inversely correlated to EICMA function. Active functioning of EICMA brings about a decrease of the retrograde blood flow in the OA and in some cases, alteration in the direction of the blood flow in that artery, namely from retrograde to antegrade. Nevertheless additional blood flow via EICMA promotes elevation of the level of the cerebral blood flow in the regions of the middle cerebral artery basin, supplied via the microarterial anastomosis.

Adult

[Regional cerebral blood flow and the infarct volume in obstruction of the internal carotid artery in relationship to the source of the collateral circulation].

The cerebral blood flow was examined by means of Obrist's 133Xe-inhalational method, cerebral angiography, and computer-aided tomography of the head in 100 patients with occlusion of the internal carotid artery. The findings obtained have revealed a correlation between the level of the compensatory collateral blood supply of the bed of the middle cerebral artery (MCA) and the source of collateral blood circulation. The authors have demonstrated the vulnerability of the MCA bed secondary to a low level of blood supply persisting despite the functioning of all pathways of the collateral circulation.

Brain

[Cerebral hemodynamics in stenoses of the internal carotid artery].

The cerebral hemodynamics was studied in 51 patients with varying severity of stenoses of the internal carotid artery (ICA) expressed in transient disorders of the cerebral blood flow or ischemic strokes. To study the cerebral blood flow (CBF), the authors used the 133Xe-inhalational method; in their analysis they also considered the findings of clinical, angiographic and computer-aided tomographic examinations, as well as the rheological parameters of the blood. It has been established that the main characteristics of the cerebral hemodynamics in patients with ICA stenoses are a moderate diffuse reduction of the CBF in both hemispheres of the brain without a clear-cut interhemispherical asymmetry, the absence of the dependence of the CBF on the degree of ICA stenoses, inverse correlation between the degree of the total narrowing of the lumen of all main arteries of the head and parameters of the CBF, as well as a sharper decrease in the CBF in cases where the total stenosis of the main arteries of the head exceeds 40%. The article deals with the pathogenesis of cerebral circulation impairments in ICA stenoses and the selection of the tactics of treating patients.

Adult

[Hemodynamic risk factors of secondary brain infarcts in patients with occlusion of the internal carotid artery].

Study of the cerebral hemodynamics in 52 patients with occlusion of the internal carotid artery made it possible to ascertain the factors responsible for a bilateral decrease in the cerebral blood flow. The identification of the causes of a decreased cerebral blood supply in this pathology may contribute to timely rational treatment of patients and to reducing the risk of repeated cerebral infarction.

Adult

[Normal values for regional cerebral blood flow using the 133Xe-inhalation method].

Using the 32-detector system and the inhalation method after W. Obrist, the authors determined normal values of the regional cerebral blood flow (RCB) in 20 healthy subjects. The method demonstrated good reproducibility which warrants its wide clinical application for RCB determination for studying the pathogenetic mechanisms of cerebral blood flow changes.

Cerebrovascular Circulation

[Radioisotope (133Xe) inhalation method of determining regional cerebral blood flow].

The modern 133(Xe) inhalational method of regional blood flow evaluation is described first in the Soviet literature. Examples of brain blood flow studied in patients with brain vascular diseases are reviewed. The data obtained illustrate the method possibilities in diagnostical and clinical problems as well as in problems of affected brain regions blood supply and function accordance. The use of a safe method with 133(Xe) in regional brain blood supply study will help solving hemodynamic and brain function problems in health and disease.

Brain Ischemia

[Clinical and echoencephalographic diagnosis of lesions of the frontal lobe in the acute period of severe cranio-cerebral injury].

An analysis of clinical and echoencephalographic studies in 100 patients permitted the author to detect a dependency between the clinical signs of frontal lobe lesions and the mechanisms of the inflicted trauma. A clarification of the character of the traumatic injury of the frontal lobe (contusion or contusion-crush) is very important inasmuch as it determines the medical tactics in relation to treatment. According to the data of the author, patients with contusions of the frontal lobes require conservative treatment, while in traumatical crushing of the frontal lobes surgical treatment may be frequently necessary.

Adolescent

[The clinical picture of acute epidural hematoma of traumatic origin].

An analysis of 100 observations permitted the authors to conclude that the basis of the clinical picture of acute epidural hematoma was the syndrome of intercranial hypertension manifesting itself in growing disturbances of consciousness, headaches, vomiting, bradycardia. The appearance of local neurological symptoms gives a possibility for a physician to orientate quickly in the pathological process localization. "A lucid period" and the initial syndrome of the acute brain dislocation often revealed in the manifestation of mydriase are typical of the clinical picture of epidural hematoma.

Acute Disease